Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50039057
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50241119(CHEMBL218166 | 7-(4-Biphenyl-3-ylmethyl-piperazin-...)
Affinity DataKi:  0.0400nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50241119(CHEMBL218166 | 7-(4-Biphenyl-3-ylmethyl-piperazin-...)
Affinity DataKi:  0.100nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50001955(APOKYN | CHEMBL53 | (Apomorphine) 6-Methyl-5,6,6a,...)
Affinity DataKi:  0.620nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  1.90nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50130293(7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50069907(1-benzyl-4-(3-hydroxyphenyl)piperazine | 3-(4-Benz...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM35254(CHEMBL715 | 2-methyl-4-(4-methylpiperazin-1-yl)-10...)
Affinity DataKi:  6.10nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50010617(Preclamol | (-)-3-(1-Propyl-piperidin-3-yl)-phenol...)
Affinity DataKi:  17.4nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM35254(CHEMBL715 | 2-methyl-4-(4-methylpiperazin-1-yl)-10...)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50308022(1-Benzyl-4-(3-hydroxyphenyl)piperidine | CHEMBL592...)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50308023(1-(3-Hydroxyphenyl)-4-propylpiperazine | 3-(4-Prop...)
Affinity DataKi:  69nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50069907(1-benzyl-4-(3-hydroxyphenyl)piperazine | 3-(4-Benz...)
Affinity DataKi:  115nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50001955(APOKYN | CHEMBL53 | (Apomorphine) 6-Methyl-5,6,6a,...)
Affinity DataKi:  244nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50308022(1-Benzyl-4-(3-hydroxyphenyl)piperidine | CHEMBL592...)
Affinity DataKi:  285nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50308024(3-(N-propylpiperidin-4-yl)phenol | CHEMBL592618)
Affinity DataKi:  349nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50308026(1-Benzyl-4-[3-(methylsulfonyl)phenyl]piperidine | ...)
Affinity DataKi:  392nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50308025(1-Benzyl-4-[3-(methylsulfonyl)phenyl]piperazine | ...)
Affinity DataKi:  431nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50308027(1-[3-(Methylsulfonyl)phenyl]-4-propylpiperazine | ...)
Affinity DataKi:  664nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50308023(1-(3-Hydroxyphenyl)-4-propylpiperazine | 3-(4-Prop...)
Affinity DataKi:  721nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50039749((S)-3-(3-(methylsulfonyl)phenyl)-1-propylpiperidin...)
Affinity DataKi:  755nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50308026(1-Benzyl-4-[3-(methylsulfonyl)phenyl]piperidine | ...)
Affinity DataKi:  841nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50308027(1-[3-(Methylsulfonyl)phenyl]-4-propylpiperazine | ...)
Affinity DataKi:  1.21E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50308025(1-Benzyl-4-[3-(methylsulfonyl)phenyl]piperazine | ...)
Affinity DataKi:  1.92E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataKi:  2.10E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50010617(Preclamol | (-)-3-(1-Propyl-piperidin-3-yl)-phenol...)
Affinity DataKi:  2.27E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50308024(3-(N-propylpiperidin-4-yl)phenol | CHEMBL592618)
Affinity DataKi:  2.57E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50039749((S)-3-(3-(methylsulfonyl)phenyl)-1-propylpiperidin...)
Affinity DataKi:  3.88E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50308028(4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine | ...)
Affinity DataKi:  7.52E+3nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at high affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Neurosearch Sweden

Curated by ChEMBL
LigandPNGBDBM50308028(4-[3-(Methylsulfonyl)phenyl]-1-propylpiperidine | ...)
Affinity DataKi:  1.76E+4nMAssay Description:Displacement of [3H]spiperone from human dopamine D2 receptor at low affinity state expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/28/2012
Entry Details Article
PubMed