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Found 16 Enz. Inhib. hit(s) with all data for entry = 50031593
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50315884((3S,8R,9S,10S,13S,14S)-10,13-dimethyl-3-phenethoxy...)
Affinity DataIC50:  57nMAssay Description:Inhibition of 17beta-HSD3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50315879(1,5-bis(4-ethoxyphenyl)penta-1,4-dien-3-one | CHEM...)
Affinity DataIC50:  70nMAssay Description:Inhibition of 17beta-HSD3 in Sprague-Dawley rat laydig cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50266759((1E,4E)-1,5-bis(4-fluorophenyl)penta-1,4-dien-3-on...)
Affinity DataIC50:  100nMAssay Description:Inhibition of 17beta-HSD3 in Sprague-Dawley rat laydig cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50241208((2E,6E)-2,6-bis(3,4,5-trimethoxybenzylidene)cycloh...)
Affinity DataIC50:  100nMAssay Description:Inhibition of 17beta-HSD3 in human testis microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50315878(2,5-bis(3-bromobenzylidene)cyclopentanone | CHEMBL...)
Affinity DataIC50:  700nMAssay Description:Inhibition of 17beta-HSD3 in Sprague-Dawley rat testis microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50315880(1,5-bis(4-(tetrahydro-2H-pyran-3-yloxy)phenyl)pent...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of 17beta-HSD3 in Sprague-Dawley rat laydig cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50241208((2E,6E)-2,6-bis(3,4,5-trimethoxybenzylidene)cycloh...)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of 17beta-HSD3 in Sprague-Dawley rat testis microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50067040(((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hept...)
Affinity DataIC50:  2.30E+3nMAssay Description:Inhibition of 17beta-HSD3 in Sprague-Dawley rat testis microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50315882(1,5-bis(4-(dimethylamino)phenyl)penta-1,4-dien-3-o...)
Affinity DataIC50:  2.40E+3nMAssay Description:Inhibition of 17beta-HSD3 in human testis microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50315883(CHEMBL1093484 | biphenyl-p-benzoquinone)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of 17beta-HSD3 in human testis microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50315881(1,5-bis(3-bromophenyl)penta-1,4-dien-3-one | CHEMB...)
Affinity DataIC50:  2.70E+3nMAssay Description:Inhibition of 17beta-HSD3 in human testis microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50266759((1E,4E)-1,5-bis(4-fluorophenyl)penta-1,4-dien-3-on...)
Affinity DataIC50:  3.30E+3nMAssay Description:Inhibition of 17beta-HSD3 in Sprague-Dawley rat testis microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50315881(1,5-bis(3-bromophenyl)penta-1,4-dien-3-one | CHEMB...)
Affinity DataIC50:  8.50E+3nMAssay Description:Inhibition of 17beta-HSD3 in Sprague-Dawley rat testis microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50067040(((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hept...)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of 17beta-HSD3 in Sprague-Dawley rat laydig cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Homo sapiens (Human))
School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50067040(((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hept...)
Affinity DataIC50:  6.73E+4nMAssay Description:Inhibition of 17beta-HSD3 in human testis microsomesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
School Of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50241208((2E,6E)-2,6-bis(3,4,5-trimethoxybenzylidene)cycloh...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of 17beta-HSD3 in Sprague-Dawley rat laydig cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed