Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50031683
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317169BDBM50317169((2'Z,3'E)-5-Nitro-5'-fluoro-indirubin-3'-oxime | C...)
Affinity DataIC50: 1.70nMAssay Description:Inhibition of CDK2/cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317171BDBM50317171((2'Z,3'E)-5-Fluoro-5'-fluoro-indirubin-3'-oxime | ...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of CDK2/cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317161BDBM50317161((2'Z,3'E)-5-Nitro-5'-hydroxy-indirubin-3'-oxime | ...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of CDK2/cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317163BDBM50317163((2'Z,3'E)-5-Fluoro-5'-hydroxy-indirubin-3'-oxime |...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of CDK2/cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317162BDBM50317162((2'Z,3'E)-5-Chloro-5'-hydroxy-indirubin-3'-oxime |...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of CDK2/cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317177BDBM50317177(5-nitroindirubin-3'-oxime | CHEMBL369303)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of CDK2/cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317170BDBM50317170((2'Z,3'E)-5-Chloro-5'-fluoro-indirubin-3'-oxime | ...)
Affinity DataIC50: 8nMAssay Description:Inhibition of CDK2/cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317164BDBM50317164((2'Z,3'E)-5-Trifluoromethoxy-5'-hydroxy-indirubin-...)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of CDK2/cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317173BDBM50317173((2'Z,3'E)-5-Nitro-5'-methyl-indirubin-3'-oxime | C...)
Affinity DataIC50: 8.70nMAssay Description:Inhibition of CDK2/cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317167BDBM50317167((2'Z,3'E)-5-Fluoro-5'-chloro-indirubin-3'-oxime | ...)
Affinity DataIC50: 10nMAssay Description:Inhibition of CDK2/cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317166BDBM50317166((2'Z,3'E)-5-Chloro-5'-chloro-indirubin-3'-oxime | ...)
Affinity DataIC50: 11nMAssay Description:Inhibition of CDK2/cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317161BDBM50317161((2'Z,3'E)-5-Nitro-5'-hydroxy-indirubin-3'-oxime | ...)
Affinity DataIC50: 13nMAssay Description:Inhibition of CDK1/cyclin B after 40 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317165BDBM50317165((2'Z,3'E)-5-Nitro-5'-chloro-indirubin-3'-oxime | C...)
Affinity DataIC50: 24nMAssay Description:Inhibition of CDK2/cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317172BDBM50317172((2'Z,3'E)-5-Trifluoromethoxy-5'-fluoro-indirubin-3...)
Affinity DataIC50: 60nMAssay Description:Inhibition of CDK2/cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317168BDBM50317168((2'Z,3'E)-5-Trifluoromethoxy-5'-chloro-indirubin-3...)
Affinity DataIC50: 76nMAssay Description:Inhibition of CDK2/cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317165BDBM50317165((2'Z,3'E)-5-Nitro-5'-chloro-indirubin-3'-oxime | C...)
Affinity DataIC50: 195nMAssay Description:Inhibition of CDK1/cyclin B after 40 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetAurora kinase A(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317161BDBM50317161((2'Z,3'E)-5-Nitro-5'-hydroxy-indirubin-3'-oxime | ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant auroraA preincubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317174BDBM50317174((2'Z,3'E)-5-Nitro-5'-methoxy-indirubin-3'-oxime | ...)
Affinity DataIC50: 2.95E+3nMAssay Description:Inhibition of CDK2/cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317161BDBM50317161((2'Z,3'E)-5-Nitro-5'-hydroxy-indirubin-3'-oxime | ...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of recombinant TrKa preincubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317175BDBM50317175((2'Z,3'E)-5-Fluoro-5'-methoxy-indirubin-3'-oxime |...)
Affinity DataIC50: 4.12E+3nMAssay Description:Inhibition of CDK2/cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317176BDBM50317176((2'Z,3'E)-5-Trifluoromethoxy-5'-methoxy-indirubin-...)
Affinity DataIC50: 8.62E+3nMAssay Description:Inhibition of CDK2/cyclin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Institute of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50317161BDBM50317161((2'Z,3'E)-5-Nitro-5'-hydroxy-indirubin-3'-oxime | ...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant IKK-beta preincubated for 15 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMed