Compile Data Set for Download or QSAR
Report error Found 92 Enz. Inhib. hit(s) with all data for entry = 50031801
LigandChemical structure of BindingDB Monomer ID 50319578BDBM50319578((2S)-(4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benz...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319577BDBM50319577(3-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benzothiad...)
Affinity DataIC50: 1nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319582BDBM50319582(4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benzothiad...)
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319580BDBM50319580((2S)-4-(2,2-Dioxido-3-phenyl-2,1,3-benzothiadiazol...)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319579BDBM50319579(4-(2,2-Dioxido-3-phenyl-2,1,3-benzothiadiazol-1(3H...)
Affinity DataIC50: 2nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319581BDBM50319581((2S)-(4-[3-(2,6-Difluorophenyl)-2,2-dioxido-2,1,3-...)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319587BDBM50319587({3-[3-(2-Fluoro-phenyl)-2,2-dioxo-2,3-dihydro-2lam...)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319575BDBM50319575((2S)-(4-[3-(2,5-Difluorophenyl)-2,2-dioxido-2,1,3-...)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319576BDBM50319576(4-(2,2-Dioxido-3-phenyl-2,1,3-benzothiadiazol-1(3H...)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319578BDBM50319578((2S)-(4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benz...)
Affinity DataIC50: 2nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 35229BDBM35229(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50319577BDBM50319577(3-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benzothiad...)
Affinity DataIC50: 2.70nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319585BDBM50319585((2R)-4-(2,2-Dioxido-3-phenyl-2,1,3-benzothiadiazol...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319575BDBM50319575((2S)-(4-[3-(2,5-Difluorophenyl)-2,2-dioxido-2,1,3-...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319583BDBM50319583((2R)-(4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benz...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 35229BDBM35229(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
Affinity DataKi:  3.40nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandChemical structure of BindingDB Monomer ID 50319581BDBM50319581((2S)-(4-[3-(2,6-Difluorophenyl)-2,2-dioxido-2,1,3-...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319583BDBM50319583((2R)-(4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benz...)
Affinity DataIC50: 4nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319580BDBM50319580((2S)-4-(2,2-Dioxido-3-phenyl-2,1,3-benzothiadiazol...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319582BDBM50319582(4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benzothiad...)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319602BDBM50319602(3-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benzothiad...)
Affinity DataIC50: 5nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319576BDBM50319576(4-(2,2-Dioxido-3-phenyl-2,1,3-benzothiadiazol-1(3H...)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319578BDBM50319578((2S)-(4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benz...)
Affinity DataIC50: 6nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319586BDBM50319586((2R)-(4-[3-(2,6-Difluorophenyl)-2,2-dioxido-2,1,3-...)
Affinity DataIC50: 6nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319587BDBM50319587({3-[3-(2-Fluoro-phenyl)-2,2-dioxo-2,3-dihydro-2lam...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319590BDBM50319590((2S)-(4-[3-(2-Chlorophenyl)-2,2-dioxido-2,1,3-benz...)
Affinity DataIC50: 8nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319585BDBM50319585((2R)-4-(2,2-Dioxido-3-phenyl-2,1,3-benzothiadiazol...)
Affinity DataIC50: 9nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319588BDBM50319588(1-(Cyclopropylamino)-4-(2,2-dioxido-3-phenyl-2,1,3...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319586BDBM50319586((2R)-(4-[3-(2,6-Difluorophenyl)-2,2-dioxido-2,1,3-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 30130BDBM30130(Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of SERT-mediated serotonin uptake in human JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319584BDBM50319584((2R)-(4-[3-(2,5-Difluorophenyl)-2,2-dioxido-2,1,3-...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319578BDBM50319578((2S)-(4-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benz...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319593BDBM50319593((2S)-(4-[3-(2,4-Difluorophenyl)-2,2-dioxido-2,1,3-...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319593BDBM50319593((2S)-(4-[3-(2,4-Difluorophenyl)-2,2-dioxido-2,1,3-...)
Affinity DataIC50: 19nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319589BDBM50319589((2S)-(4-[3-(3-Methoxyphenyl)-2,2-dioxido-2,1,3-ben...)
Affinity DataIC50: 19nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319596BDBM50319596((2S)-(4-[3-(2-Methylphenyl)-2,2-dioxido-2,1,3-benz...)
Affinity DataIC50: 22nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50005536BDBM50005536(Mazanor | 42-548 | 5-(4-Chloro-phenyl)-2,5-dihydro...)
Affinity DataKi:  22.1nMAssay Description:Displacement of [3H]WIN-35428 from human recombinant DAT expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319589BDBM50319589((2S)-(4-[3-(3-Methoxyphenyl)-2,2-dioxido-2,1,3-ben...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319590BDBM50319590((2S)-(4-[3-(2-Chlorophenyl)-2,2-dioxido-2,1,3-benz...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319584BDBM50319584((2R)-(4-[3-(2,5-Difluorophenyl)-2,2-dioxido-2,1,3-...)
Affinity DataIC50: 34nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319595BDBM50319595((2S)-(4-[3-(3,4-Difluorophenyl)-2,2-dioxido-2,1,3-...)
Affinity DataIC50: 36nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319595BDBM50319595((2S)-(4-[3-(3,4-Difluorophenyl)-2,2-dioxido-2,1,3-...)
Affinity DataIC50: 43nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319594BDBM50319594((2R)-(4-[3-(2-Chlorophenyl)-2,2-dioxido-2,1,3-benz...)
Affinity DataIC50: 48nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319599BDBM50319599((2S)-(4-[3-(4-Fluorophenyl)-2,2-dioxido-2,1,3-benz...)
Affinity DataIC50: 51nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319604BDBM50319604((2R)-3-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benzo...)
Affinity DataIC50: 57nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319594BDBM50319594((2R)-(4-[3-(2-Chlorophenyl)-2,2-dioxido-2,1,3-benz...)
Affinity DataIC50: 61nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319596BDBM50319596((2S)-(4-[3-(2-Methylphenyl)-2,2-dioxido-2,1,3-benz...)
Affinity DataIC50: 64nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319602BDBM50319602(3-[3-(2-Fluorophenyl)-2,2-dioxido-2,1,3-benzothiad...)
Affinity DataIC50: 72nMAssay Description:Inhibition of human NET-mediated norepinephrine uptake in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319597BDBM50319597((2R)-(4-[3-(3-Methoxyphenyl)-2,2-dioxido-2,1,3-ben...)
Affinity DataIC50: 80nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50319600BDBM50319600(2,2-Difluoro-3-[3-(2-fluorophenyl)-2,2-dioxido-2,1...)
Affinity DataIC50: 94nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in MDCK-Net6 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMed
Displayed 1 to 50 (of 92 total ) | Next | Last >>
Jump to: