Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50039184
TargetTYR_PHOSPHATASE_2 domain-containing protein(Mycobacterium tuberculosis (strain CDC 1551 / Oshk...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50320829((oxalylamino-methylene)-thiophenesulfonamide | CHE...)
Affinity DataIC50: 440nMAssay Description:Inhibition of N-terminal histidine-tagged Mycobacterium tuberculosis PTPB expressed in Escherichia coli BL21 (DE3) after 45 mins by fluorescence assa...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193040(1-(3,4-dimethoxyphenyl)-3-(naphthalen-2-yl)prop-2-...)
Affinity DataKi:  4.90E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA-mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193042((2E)-1-(2',5'-dimethoxyphenyl)-3-(2-naphthyl)-2-pr...)
Affinity DataKi:  5.40E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA-mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193042((2E)-1-(2',5'-dimethoxyphenyl)-3-(2-naphthyl)-2-pr...)
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA after 20 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50246224((2E)-1-(2'-hydroxyphenyl)-3-(1-naphthyl)-2-propen-...)
Affinity DataKi:  9.10E+3nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA-mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50320828(1-(3'-methoxy-4'-hydroxyphenyl)-3-(2-naphthyl)-2-p...)
Affinity DataKi:  1.79E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA-mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193009((2E)-1-(2',5'-dimethoxyphenyl)-3-(1-naphthyl)-2-pr...)
Affinity DataKi:  2.13E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA-mediated pNPP hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193040(1-(3,4-dimethoxyphenyl)-3-(naphthalen-2-yl)prop-2-...)
Affinity DataIC50: 2.31E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA after 20 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50159781(molybdate | CHEMBL183648)
Affinity DataIC50: 2.45E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50284960(trihydrogen(tetraoxidovanadate)trihydroxidooxidova...)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50080994(sodium tungstate | CHEMBL85943)
Affinity DataIC50: 3.08E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193009((2E)-1-(2',5'-dimethoxyphenyl)-3-(1-naphthyl)-2-pr...)
Affinity DataIC50: 3.95E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA after 20 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50246224((2E)-1-(2'-hydroxyphenyl)-3-(1-naphthyl)-2-propen-...)
Affinity DataIC50: 5.02E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA after 20 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetLow molecular weight protein-tyrosine phosphatase A(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50320828(1-(3'-methoxy-4'-hydroxyphenyl)-3-(2-naphthyl)-2-p...)
Affinity DataIC50: 5.37E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis PTPA after 20 mins by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50320828(1-(3'-methoxy-4'-hydroxyphenyl)-3-(2-naphthyl)-2-p...)
Affinity DataIC50: 1.23E+5nMAssay Description:Inhibition of human PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193042((2E)-1-(2',5'-dimethoxyphenyl)-3-(2-naphthyl)-2-pr...)
Affinity DataIC50: 1.45E+5nMAssay Description:Inhibition of human PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50246224((2E)-1-(2'-hydroxyphenyl)-3-(1-naphthyl)-2-propen-...)
Affinity DataIC50: 1.58E+5nMAssay Description:Inhibition of human PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193009((2E)-1-(2',5'-dimethoxyphenyl)-3-(1-naphthyl)-2-pr...)
Affinity DataIC50: 2.14E+5nMAssay Description:Inhibition of human PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Universidade Federal De Santa Catarina

Curated by ChEMBL
LigandPNGBDBM50193040(1-(3,4-dimethoxyphenyl)-3-(naphthalen-2-yl)prop-2-...)
Affinity DataIC50: 1.26E+6nMAssay Description:Inhibition of human PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2012
Entry Details Article
PubMed