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Found 6 Enz. Inhib. hit(s) with all data for entry = 50031839
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Putra Malaysia

Curated by ChEMBL
LigandPNGBDBM50320314(5-(Naphthalen-1-ylmethyl)-3-(piperazin-1-ylmethyl)...)
Affinity DataIC50:  870nMAssay Description:Inhibition of mushroom tyrosinase preincubated for 5 mins before addition of L-DOPA measured after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Putra Malaysia

Curated by ChEMBL
LigandPNGBDBM50320310(1-ylmethyl)-3-(piperidin-1-ylmethyl)-1,3,4-oxadiaz...)
Affinity DataIC50:  970nMAssay Description:Inhibition of mushroom tyrosinase preincubated for 5 mins before addition of L-DOPA measured after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Putra Malaysia

Curated by ChEMBL
LigandPNGBDBM50320312((Naphthalen-1-ylmethyl)-3-(pyrrolidin-1-ylmethyl)-...)
Affinity DataIC50:  1.33E+3nMAssay Description:Inhibition of mushroom tyrosinase preincubated for 5 mins before addition of L-DOPA measured after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Putra Malaysia

Curated by ChEMBL
LigandPNGBDBM50320311((Morpholinomethyl)-5-(naphthalen-1-ylmethyl)-1,3,4...)
Affinity DataIC50:  1.34E+3nMAssay Description:Inhibition of mushroom tyrosinase preincubated for 5 mins before addition of L-DOPA measured after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Putra Malaysia

Curated by ChEMBL
LigandPNGBDBM50320313(3-((4-Methylpiperazin-1-yl)methyl)-5-(naphthalen-1...)
Affinity DataIC50:  1.49E+3nMAssay Description:Inhibition of mushroom tyrosinase preincubated for 5 mins before addition of L-DOPA measured after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 2(Agaricus bisporus (Common mushroom))
University Putra Malaysia

Curated by ChEMBL
LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  9.18E+3nMAssay Description:Inhibition of mushroom tyrosinase preincubated for 5 mins before addition of L-DOPA measured after 10 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed