Compile Data Set for Download or QSAR
maximum 50k data
Found 38 Enz. Inhib. hit(s) with all data for entry = 50032598
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331736(2-((R)-9-((S)-1-(3-chlorophenyl)ethyl)-6-fluoro-8-...)
Affinity DataKi:  0.310nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331738(2-((R)-6-fluoro-9-((S)-1-(4-fluorophenyl)ethyl)-8-...)
Affinity DataKi:  0.330nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331733(2-((R)-9-((S)-1-(3,4-dichlorophenyl)ethyl)-6-fluor...)
Affinity DataKi:  0.330nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331742(2-((R)-9-((R)-1-(4-chlorophenyl)-2-fluoroethyl)-6-...)
Affinity DataKi:  0.360nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331735(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-phenyl...)
Affinity DataKi:  0.360nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331732(2-((R)-9-((S)-1-(4-chloro-3-fluorophenyl)ethyl)-6-...)
Affinity DataKi:  0.380nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331739(2-((R)-9-((S)-1-(4-bromophenyl)ethyl)-6-fluoro-8-(...)
Affinity DataKi:  0.380nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331743(2-((R)-9-((R)-1-(4-chlorophenyl)-2,2-difluoroethyl...)
Affinity DataKi:  0.390nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331734(2-((R)-9-((S)-1-(4-chloro-2-fluorophenyl)ethyl)-6-...)
Affinity DataKi:  0.410nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331737(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-(4-(tr...)
Affinity DataKi:  0.430nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331740(2-((R)-9-((S)-1-(4-cyanophenyl)ethyl)-6-fluoro-8-(...)
Affinity DataKi:  0.510nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331731(2-((R)-9-((S)-1-(4-chlorophenyl)ethyl)-6-fluoro-8-...)
Affinity DataKi:  0.75nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331730((+/-)-2-(9-(4-chlorobenzyl)-6-fluoro-8-(methylsulf...)
Affinity DataKi:  0.890nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331729(2-(9-(1-(4-chlorophenyl)ethyl)-6-fluoro-8-(methyls...)
Affinity DataKi:  1.30nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331729(2-(9-(1-(4-chlorophenyl)ethyl)-6-fluoro-8-(methyls...)
Affinity DataKi:  1.30nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331730((+/-)-2-(9-(4-chlorobenzyl)-6-fluoro-8-(methylsulf...)
Affinity DataKi:  2.51nMAssay Description:Antagonist activity at prostanoid TP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331741(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-(4-(me...)
Affinity DataKi:  16.5nMAssay Description:Antagonist activity at prostanoid DP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331740(2-((R)-9-((S)-1-(4-cyanophenyl)ethyl)-6-fluoro-8-(...)
Affinity DataKi:  93nMAssay Description:Antagonist activity at prostanoid TP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331738(2-((R)-6-fluoro-9-((S)-1-(4-fluorophenyl)ethyl)-8-...)
Affinity DataKi:  100nMAssay Description:Antagonist activity at prostanoid TP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331739(2-((R)-9-((S)-1-(4-bromophenyl)ethyl)-6-fluoro-8-(...)
Affinity DataKi:  106nMAssay Description:Antagonist activity at prostanoid TP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331733(2-((R)-9-((S)-1-(3,4-dichlorophenyl)ethyl)-6-fluor...)
Affinity DataKi:  112nMAssay Description:Antagonist activity at prostanoid TP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331742(2-((R)-9-((R)-1-(4-chlorophenyl)-2-fluoroethyl)-6-...)
Affinity DataKi:  130nMAssay Description:Antagonist activity at prostanoid TP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331743(2-((R)-9-((R)-1-(4-chlorophenyl)-2,2-difluoroethyl...)
Affinity DataKi:  138nMAssay Description:Antagonist activity at prostanoid TP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331731(2-((R)-9-((S)-1-(4-chlorophenyl)ethyl)-6-fluoro-8-...)
Affinity DataKi:  184nMAssay Description:Antagonist activity at prostanoid TP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331732(2-((R)-9-((S)-1-(4-chloro-3-fluorophenyl)ethyl)-6-...)
Affinity DataKi:  200nMAssay Description:Antagonist activity at prostanoid TP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331734(2-((R)-9-((S)-1-(4-chloro-2-fluorophenyl)ethyl)-6-...)
Affinity DataKi:  270nMAssay Description:Antagonist activity at prostanoid TP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331736(2-((R)-9-((S)-1-(3-chlorophenyl)ethyl)-6-fluoro-8-...)
Affinity DataKi:  292nMAssay Description:Antagonist activity at prostanoid TP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331737(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-(4-(tr...)
Affinity DataKi:  338nMAssay Description:Antagonist activity at prostanoid TP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331735(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-phenyl...)
Affinity DataKi:  362nMAssay Description:Antagonist activity at prostanoid TP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP3 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331737(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-(4-(tr...)
Affinity DataKi:  830nMAssay Description:Binding affinity to prostanoid receptor EP3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331741(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-(4-(me...)
Affinity DataKi:  1.48E+3nMAssay Description:Antagonist activity at prostanoid TP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331737(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-(4-(tr...)
Affinity DataKi:  2.27E+3nMAssay Description:Binding affinity to prostanoid receptor EP2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin F2-alpha receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331737(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-(4-(tr...)
Affinity DataKi:  4.32E+3nMAssay Description:Binding affinity to prostanoid receptor FP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP1 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331737(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-(4-(tr...)
Affinity DataKi:  4.59E+3nMAssay Description:Binding affinity to prostanoid receptor EP1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331737(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-(4-(tr...)
Affinity DataKi:  6.61E+3nMAssay Description:Binding affinity to prostanoid receptor EP4 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstacyclin receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331737(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-(4-(tr...)
Affinity DataKi:  1.55E+4nMAssay Description:Binding affinity to prostanoid receptor IP receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331737(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-(4-(tr...)
Affinity DataIC50:  2.5nMAssay Description:Antagonist activity at prostanoid DP1 receptor in human platelet assessed as inhibition of PGD2 induced accumulation of cAMPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50331737(2-((R)-6-fluoro-8-(methylsulfonyl)-9-((S)-1-(4-(tr...)
Affinity DataIC50:  1.94E+4nMAssay Description:Antagonist activity at TP receptor in human platelet assessed as thromboxane A2- induced platelet aggregationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed