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Found 73 Enz. Inhib. hit(s) with all data for entry = 50039340
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335039(2-Amino-5-cyclopropylmethyl-4-[2-(5-phosphono)fura...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335036(2-Amino-5-cyclobutyl-4-[2-(5-phosphono)furanyl]thi...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335069(2-Amino-5-(2-naphthyl)-4-[2-(5-phosphono)furanyl]t...)
Affinity DataIC50:  12nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335065(2-Amino-5-(4-chlorophenyl)-4-[2-(5-phosphono)furan...)
Affinity DataIC50:  13nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335054(2-Amino-4-[2-(5-phosphono)furanyl]-5-ethoxycarbony...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335063(2-Amino-5-(4-methoxycarbonylphenyl)-4-[2-(5-phosph...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335057(5-(2-amino-5-phenylthiazol-4-yl)furan-2-ylphosphon...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335055(2-Amino-5-benzyloxycarbonyl-4-[2-(5-phosphono)fura...)
Affinity DataIC50:  15nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335048(2-Amino-5-(N-morpholinyl)-4-[2-(5-phosphono)furany...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335083(2-Amino-4-[2-(5-phosphono)furanyl]-5-propylsulfany...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335064(2-Amino-5-(4-fluorophenyl)-4-[2-(5-phosphono)furan...)
Affinity DataIC50:  16nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335041(2-Amino-5-cyclohexylmethyl-4-[2-(5-phosphono)furan...)
Affinity DataIC50:  18nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335037(2-Amino-5-cyclopentyl-4-[2-(5-phosphono)furanyl]th...)
Affinity DataIC50:  19nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335040(2-Amino-5-cyclopentylmethyl-4-[2-(5-phosphono)fura...)
Affinity DataIC50:  20nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335061(2-Amino-5-(4-methylthiophenyl)-4-[2-(5-phosphono)f...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335059(2-Amino-5-(3-methoxyphenyl)-4-[2-(5-phosphono)fura...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335038(2-Amino-5-cyclohexyl-4-[2-(5-phosphono)furanyl]thi...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335060(2-Amino-5-(4-methoxyphenyl)-4-[2-(5-phosphono)fura...)
Affinity DataIC50:  22nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335050(2-Amino-5-isopropylthio-4-[2-(5-phosphono)furanyl]...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335051(2-Amino-5-tert-butylthio-4-[2-(5-phosphono)furanyl...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50293594(5-(2-amino-5-isobutylthiazol-4-yl)furan-2-ylphosph...)
Affinity DataIC50:  25nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335034(2-Amino-5-(2,2,2-trifluoroethyl)-4-[2-(5-phosphono...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335033(2-Amino-5-isopropyl-4-[2-(5-phosphono)furanyl]thia...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335066(2-Amino-5-(4-acetylphenyl)-4-[2-(5-phosphono)furan...)
Affinity DataIC50:  32nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335049(2-Amino-5-ethylthio-4-[2-(5-phosphono)furanyl]thia...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335068(2-Amino-5-(4-phenylphenyl)-4-[2-(5-phosphono)furan...)
Affinity DataIC50:  34nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335070(2-Amino-5-(2-furanyl)-4-[2-(5-phosphono)furanyl]th...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335067(2-Amino-5-(4-methanesulfonyl)-4-[2-(5-phosphono)fu...)
Affinity DataIC50:  41nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335058(2-Amino-5-(2-methoxyphenyl)-4-[2-(5-phosphono)fura...)
Affinity DataIC50:  43nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335071(2-Amino-5-(2-thienyl)-4-[2-(5-phosphono)furanyl]th...)
Affinity DataIC50:  44nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335075(2-Amino-5-propyl-4-phosphonomethoxycarbonylthiazol...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335046(2-Amino-5-bromo-4-[2-(5-phosphono)furanyl]thiazole...)
Affinity DataIC50:  50nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335035(2-Amino-5-neopentyl-4-[2-(5-phosphono)furanyl]thia...)
Affinity DataIC50:  57nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335042(2-Amino-5-benzyl-4-[2-(5-phosphono)furanyl]thiazol...)
Affinity DataIC50:  59nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335045(2-Amino-5-chloro-4-[2-(5-phosphono)furanyl]thiazol...)
Affinity DataIC50:  70nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335082(2-Amino-5-phenyl-4-[1-(4-fluoro-3-phosphono)phenyl...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335090(2-Bromo-5-isobutyl-4-[2-(5-phosphono)furanyl]thiaz...)
Affinity DataIC50:  80nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335062(2-Amino-5-(4-tert-butylphenyl)-4-[2-(5-phosphono)f...)
Affinity DataIC50:  88nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50303854(5-(4-amino-7-ethyl-5-fluoro-1-isobutyl-1H-benzo[d]...)
Affinity DataIC50:  90nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335047(2-Amino-5-iodo-4-[2-(5-phosphono)furanyl]thiazole ...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335084(2-Methyl-5-isobutyl-4-[2-(5-phosphono)furanyl]-thi...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335031(2-Amino-5-hydroxymethyl-4-[2-(5-phosphono)furanyl]...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335080(2-Amino-5-propyl-4-[1-(4-methyl-3-phosphono)phenyl...)
Affinity DataIC50:  135nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335043(2-Amino-5-[(4-morpholinyl)methyl]-4-[2-(5-phosphon...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335089(2-Chloro-5-isobutyl-4-[2-(5-phosphono)furanyl]thia...)
Affinity DataIC50:  180nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335081(2-Amino-5-isopropyl-4-[1-(4-methoxy-3-phosphono)ph...)
Affinity DataIC50:  210nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335087(2-Hydroxymethyl-5-isobutyl-4-[2-(5-phosphono)furan...)
Affinity DataIC50:  220nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335079(2-Amino-5-propyl-4-[1-(3-phosphono)phenyl]thiazole...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335052(2-Amino-5-phenylthio-4-[2-(5-phosphono)furanyl]thi...)
Affinity DataIC50:  300nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335085(2-Ethyl-5-isobutyl-4-[2-(5-phosphono)furanyl]thiaz...)
Affinity DataIC50:  400nMAssay Description:Inhibition of human liver FBPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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