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Found 37 Enz. Inhib. hit(s) with all data for entry = 50032989
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337557((S)-6-(2-(2-methoxyphenyl)morpholino)-1-methyl-4-(...)
Affinity DataIC50:  6.10nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337556(6-(4-hydroxy-4-phenylpiperidin-1-yl)-1-methyl-4-(p...)
Affinity DataIC50:  8.5nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50272192(4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(1...)
Affinity DataIC50:  17.2nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337548(6-(2-methoxyphenethylamino)-1-methyl-4-(pyrimidin-...)
Affinity DataIC50:  17.4nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337544(6-(diethylamino)-1-methyl-4-(pyrimidin-4-yl)pyridi...)
Affinity DataIC50:  50.1nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337555(6-(4-(2-methoxyphenyl)piperidin-1-yl)-1-methyl-4-(...)
Affinity DataIC50:  51nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337545(1-methyl-6-(piperidin-1-yl)-4-(pyrimidin-4-yl)pyri...)
Affinity DataIC50:  62nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337558((R)-6-(2-(2-methoxyphenyl)morpholino)-1-methyl-4-(...)
Affinity DataIC50:  62.8nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337554(6-(3-(2-methoxyphenyl)piperidin-1-yl)-1-methyl-4-(...)
Affinity DataIC50:  84.1nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337559(1-methyl-6-(3-phenylpiperidin-1-yl)-4-(pyrimidin-4...)
Affinity DataIC50:  115nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337553(6-((2-methoxyphenethyl)(methyl)amino)-1-methyl-4-(...)
Affinity DataIC50:  133nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity protein kinase CLK1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50272192(4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(1...)
Affinity DataIC50:  210nMAssay Description:Inhibition of CLK1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337546(1-methyl-6-morpholino-4-(pyrimidin-4-yl)pyridin-2(...)
Affinity DataIC50:  233nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337551(6-(2-methoxybenzylamino)-1-methyl-4-(pyrimidin-4-y...)
Affinity DataIC50: >252nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337552(6-(3-(2-methoxyphenyl)propylamino)-1-methyl-4-(pyr...)
Affinity DataIC50: >260nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337549(6-(3-methoxyphenethylamino)-1-methyl-4-(pyrimidin-...)
Affinity DataIC50: >401nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337547(1-methyl-6-(phenethylamino)-4-(pyrimidin-4-yl)pyri...)
Affinity DataIC50: >592nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337556(6-(4-hydroxy-4-phenylpiperidin-1-yl)-1-methyl-4-(p...)
Affinity DataIC50:  610nMAssay Description:Inhibition of human GSK3beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337550(6-(4-methoxyphenethylamino)-1-methyl-4-(pyrimidin-...)
Affinity DataIC50: >731nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337548(6-(2-methoxyphenethylamino)-1-methyl-4-(pyrimidin-...)
Affinity DataIC50:  800nMAssay Description:Inhibition of human GSK3beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337557((S)-6-(2-(2-methoxyphenyl)morpholino)-1-methyl-4-(...)
Affinity DataIC50:  840nMAssay Description:Inhibition of human GSK3beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337543(1-methyl-6-phenyl-4-(pyrimidin-4-yl)pyridin-2(1H)-...)
Affinity DataIC50: >894nMAssay Description:Inhibition of human recombinant GSK3beta expressed in baculovirus infected SF9 cells after 60 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337545(1-methyl-6-(piperidin-1-yl)-4-(pyrimidin-4-yl)pyri...)
Affinity DataIC50: >910nMAssay Description:Inhibition of human GSK3beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337558((R)-6-(2-(2-methoxyphenyl)morpholino)-1-methyl-4-(...)
Affinity DataIC50:  1.53E+3nMAssay Description:Inhibition of human GSK3beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337553(6-((2-methoxyphenethyl)(methyl)amino)-1-methyl-4-(...)
Affinity DataIC50:  1.69E+3nMAssay Description:Inhibition of human GSK3beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337544(6-(diethylamino)-1-methyl-4-(pyrimidin-4-yl)pyridi...)
Affinity DataIC50:  2.21E+3nMAssay Description:Inhibition of human GSK3beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337554(6-(3-(2-methoxyphenyl)piperidin-1-yl)-1-methyl-4-(...)
Affinity DataIC50:  2.32E+3nMAssay Description:Inhibition of human GSK3beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337555(6-(4-(2-methoxyphenyl)piperidin-1-yl)-1-methyl-4-(...)
Affinity DataIC50:  3.21E+3nMAssay Description:Inhibition of human GSK3beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337559(1-methyl-6-(3-phenylpiperidin-1-yl)-4-(pyrimidin-4...)
Affinity DataIC50:  4.64E+3nMAssay Description:Inhibition of human GSK3beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337546(1-methyl-6-morpholino-4-(pyrimidin-4-yl)pyridin-2(...)
Affinity DataIC50: >5.04E+3nMAssay Description:Inhibition of human GSK3beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50272192(4-(4-hydroxy-3-methylphenyl)-6-phenylpyrimidin-2(1...)
Affinity DataIC50: >5.28E+3nMAssay Description:Inhibition of human GSK3beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337551(6-(2-methoxybenzylamino)-1-methyl-4-(pyrimidin-4-y...)
Affinity DataIC50: >9.00E+3nMAssay Description:Inhibition of human GSK3beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337549(6-(3-methoxyphenethylamino)-1-methyl-4-(pyrimidin-...)
Affinity DataIC50: >9.00E+3nMAssay Description:Inhibition of human GSK3beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337550(6-(4-methoxyphenethylamino)-1-methyl-4-(pyrimidin-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human GSK3beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337547(1-methyl-6-(phenethylamino)-4-(pyrimidin-4-yl)pyri...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human GSK3beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337543(1-methyl-6-phenyl-4-(pyrimidin-4-yl)pyridin-2(1H)-...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human GSK3beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50337552(6-(3-(2-methoxyphenyl)propylamino)-1-methyl-4-(pyr...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human GSK3beta expressed in CHO AA8 cells co-expressing human tau protein after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed