Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 8165
TargetProstaglandin G/H synthase 2(Sheep)
Jamia Hamdard University

LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 90nMpH: 8.0 T: 2°CAssay Description:Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Jamia Hamdard University

LigandPNGBDBM235663(3-[5-(2,4-Dichloro-phenyl)-[1,3,4]oxadiazol-2-yl]-...)
Affinity DataIC50: 400nMpH: 8.0 T: 2°CAssay Description:Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Jamia Hamdard University

LigandPNGBDBM235662(3-(5-p-Tolyl-[1,3,4]oxadiazol-2-yl)-chromen-2-one ...)
Affinity DataIC50: 1.18E+3nMpH: 8.0 T: 2°CAssay Description:Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Jamia Hamdard University

LigandPNGBDBM235661(3-[5-(4-Chloro-phenyl)-[1,3,4]oxadiazol-2-yl]-chro...)
Affinity DataIC50: 1.20E+3nMpH: 8.0 T: 2°CAssay Description:Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Jamia Hamdard University

LigandPNGBDBM235660(3-(5-Phenyl-[1,3,4]oxadiazol-2-yl)-chromen-2-one (...)
Affinity DataIC50: 8.70E+3nMpH: 8.0 T: 2°CAssay Description:Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Jamia Hamdard University

LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 3.05E+4nMpH: 8.0 T: 2°CAssay Description:Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Jamia Hamdard University

LigandPNGBDBM235661(3-[5-(4-Chloro-phenyl)-[1,3,4]oxadiazol-2-yl]-chro...)
Affinity DataIC50: 3.50E+4nMpH: 8.0 T: 2°CAssay Description:Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Jamia Hamdard University

LigandPNGBDBM235665(3-(5-o-Tolylamino-[1,3,4]oxadiazol-2-yl)-chromen-2...)
Affinity DataIC50: 3.66E+4nMpH: 8.0 T: 2°CAssay Description:Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Jamia Hamdard University

LigandPNGBDBM235663(3-[5-(2,4-Dichloro-phenyl)-[1,3,4]oxadiazol-2-yl]-...)
Affinity DataIC50: 4.16E+4nMpH: 8.0 T: 2°CAssay Description:Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Jamia Hamdard University

LigandPNGBDBM235665(3-(5-o-Tolylamino-[1,3,4]oxadiazol-2-yl)-chromen-2...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Jamia Hamdard University

LigandPNGBDBM235666(4-Chloro-N-[5-(2-oxo-2H-chromen-3-yl)-[1,3,4]oxadi...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Jamia Hamdard University

LigandPNGBDBM235664(3-[5-(4-Chloro-phenylamino)-[1,3,4]oxadiazol-2-yl]...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Jamia Hamdard University

LigandPNGBDBM235662(3-(5-p-Tolyl-[1,3,4]oxadiazol-2-yl)-chromen-2-one ...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Jamia Hamdard University

LigandPNGBDBM235660(3-(5-Phenyl-[1,3,4]oxadiazol-2-yl)-chromen-2-one (...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Jamia Hamdard University

LigandPNGBDBM235666(4-Chloro-N-[5-(2-oxo-2H-chromen-3-yl)-[1,3,4]oxadi...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
Jamia Hamdard University

LigandPNGBDBM235664(3-[5-(4-Chloro-phenylamino)-[1,3,4]oxadiazol-2-yl]...)
Affinity DataIC50: 1.00E+5nMpH: 8.0 T: 2°CAssay Description:Selected 1,3,4-oxadiazole derivatives (4a, 4b, 4c, 4e, 6b, 6e, 8b) were tested for their ability to inhibit COX-1 and COX-2 using a COX-(ovine) inhib...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/29/2017
Entry Details Article
PubMed