Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50004520
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 83449BDBM83449(cid_9795678 | PHENCYCLIDINE | SMR001338811 | Phenc...)
Affinity DataIC50: 398nMAssay Description:Inhibition of human recombinant NR1/NR2A receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50044140BDBM50044140(2-(2-Chloro-phenyl)-2-methylamino-cyclohexanone(Ke...)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human recombinant NR1/NR2A receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 83449BDBM83449(cid_9795678 | PHENCYCLIDINE | SMR001338811 | Phenc...)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of human recombinant NR1/NR2B receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483655BDBM50483655(CHEMBL1760304)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human recombinant NR1/NR2A receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483659BDBM50483659(CHEMBL1760306)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of human recombinant NR1/NR2A receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483651BDBM50483651(CHEMBL1760310)
Affinity DataIC50: 3.16E+3nMAssay Description:Inhibition of human recombinant NR1/NR2A receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483661BDBM50483661(CHEMBL1760302)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of human recombinant NR1/NR2A receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50044140BDBM50044140(2-(2-Chloro-phenyl)-2-methylamino-cyclohexanone(Ke...)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of human recombinant NR1/NR2B receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483658BDBM50483658(CHEMBL1760305)
Affinity DataIC50: 5.01E+3nMAssay Description:Inhibition of human recombinant NR1/NR2A receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483659BDBM50483659(CHEMBL1760306)
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of human recombinant NR1/NR2B receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483660BDBM50483660(CHEMBL1760314)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant NR1/NR2A receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483661BDBM50483661(CHEMBL1760302)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of human recombinant NR1/NR2B receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483655BDBM50483655(CHEMBL1760304)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant NR1/NR2B receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483660BDBM50483660(CHEMBL1760314)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant NR1/NR2B receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483650BDBM50483650(CHEMBL1760309)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of human recombinant NR1/NR2A receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483649BDBM50483649(CHEMBL1760307)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of human recombinant NR1/NR2A receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483658BDBM50483658(CHEMBL1760305)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of human recombinant NR1/NR2B receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483657BDBM50483657(CHEMBL1760312)
Affinity DataIC50: 3.98E+4nMAssay Description:Inhibition of human recombinant NR1/NR2A receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483652BDBM50483652(CHEMBL1760311)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of human recombinant NR1/NR2B receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483654BDBM50483654(CHEMBL1760303)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of human recombinant NR1/NR2B receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483656BDBM50483656(CHEMBL1760308)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of human recombinant NR1/NR2A receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483654BDBM50483654(CHEMBL1760303)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of human recombinant NR1/NR2A receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483652BDBM50483652(CHEMBL1760311)
Affinity DataIC50: 5.01E+4nMAssay Description:Inhibition of human recombinant NR1/NR2A receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483649BDBM50483649(CHEMBL1760307)
Affinity DataIC50: 6.31E+4nMAssay Description:Inhibition of human recombinant NR1/NR2B receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483650BDBM50483650(CHEMBL1760309)
Affinity DataIC50: 1.58E+5nMAssay Description:Inhibition of human recombinant NR1/NR2B receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483651BDBM50483651(CHEMBL1760310)
Affinity DataIC50: 2.51E+5nMAssay Description:Inhibition of human recombinant NR1/NR2B receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483653BDBM50483653(CHEMBL1760313)
Affinity DataIC50: 2.51E+5nMAssay Description:Inhibition of human recombinant NR1/NR2B receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2A(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483653BDBM50483653(CHEMBL1760313)
Affinity DataIC50: 2.51E+5nMAssay Description:Inhibition of human recombinant NR1/NR2A receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483656BDBM50483656(CHEMBL1760308)
Affinity DataIC50: 2.51E+5nMAssay Description:Inhibition of human recombinant NR1/NR2B receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetGlutamate receptor ionotropic, NMDA 1/2B(Human)
Glaxosmithkline Medicines Research Centre

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50483657BDBM50483657(CHEMBL1760312)
Affinity DataIC50: 2.51E+5nMAssay Description:Inhibition of human recombinant NR1/NR2B receptor expressed in U2OS assessed as change in intracellular calcium level by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed