Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50033209
TargetProstaglandin G/H synthase 2(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50341443((Z)-N-(3-Chlorophenyl)-2-(4-((2,4-dioxothiazolidin...)
Affinity DataIC50: 4.16E+3nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW 264.7 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50341445((Z)-N-(3,4-Difluorophenyl)-2-(4-((2,4-dioxothiazol...)
Affinity DataIC50: 7.12E+3nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW 264.7 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50341443((Z)-N-(3-Chlorophenyl)-2-(4-((2,4-dioxothiazolidin...)
Affinity DataIC50: 8.66E+3nMAssay Description:Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse RAW 264.7 cells treated 2 hrs before LPS challenge measured after 18 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50341445((Z)-N-(3,4-Difluorophenyl)-2-(4-((2,4-dioxothiazol...)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse RAW 264.7 cells treated 2 hrs before LPS challenge measured after 18 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50341444((Z)-N-(3,5-Dichlorophenyl)-2-(4-((2,4-dioxothiazol...)
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW 264.7 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 1.54E+4nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW 264.7 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 2(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50341446((Z)-2-(4-((2,4-Dioxothiazolidin-5-ylidene)methyl)p...)
Affinity DataIC50: 1.61E+4nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW 264.7 cells after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50341446((Z)-2-(4-((2,4-Dioxothiazolidin-5-ylidene)methyl)p...)
Affinity DataIC50: 2.09E+4nMAssay Description:Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse RAW 264.7 cells treated 2 hrs before LPS challenge measured after 18 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse RAW 264.7 cells treated 2 hrs before LPS challenge measured after 18 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50341443((Z)-N-(3-Chlorophenyl)-2-(4-((2,4-dioxothiazolidin...)
Affinity DataIC50: 2.36E+4nMAssay Description:Inhibition of iNOS in LPS-stimulated mouse RAW 264.7 cells after 2 hrs by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50341444((Z)-N-(3,5-Dichlorophenyl)-2-(4-((2,4-dioxothiazol...)
Affinity DataIC50: 2.61E+4nMAssay Description:Inhibition of iNOS-mediated nitric oxide production in LPS-stimulated mouse RAW 264.7 cells treated 2 hrs before LPS challenge measured after 18 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50341445((Z)-N-(3,4-Difluorophenyl)-2-(4-((2,4-dioxothiazol...)
Affinity DataIC50: 3.41E+4nMAssay Description:Inhibition of iNOS in LPS-stimulated mouse RAW 264.7 cells after 2 hrs by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50341446((Z)-2-(4-((2,4-Dioxothiazolidin-5-ylidene)methyl)p...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of iNOS in LPS-stimulated mouse RAW 264.7 cells after 2 hrs by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 4.89E+4nMAssay Description:Inhibition of iNOS in LPS-stimulated mouse RAW 264.7 cells after 2 hrs by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Mouse)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50341444((Z)-N-(3,5-Dichlorophenyl)-2-(4-((2,4-dioxothiazol...)
Affinity DataIC50: 5.74E+4nMAssay Description:Inhibition of iNOS in LPS-stimulated mouse RAW 264.7 cells after 2 hrs by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMed