Compile Data Set for Download or QSAR
maximum 50k data
Found 7 Enz. Inhib. hit(s) with all data for entry = 50039412
TargetProtein kinase C alpha type(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human PKCalpha activity using kemptide as a substrate in presence of 50 uM ATP by mass spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  33nMAssay Description:Inhibition of PKA activity using neurogranin as a substrate in presence of 50 uM ATP by mass spectrometryMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50342212(1-[1-(3-Dimethylaminopropyl)-1H-indol-3-yl]-3-(4-p...)
Affinity DataIC50:  95nMAssay Description:Inhibition of human PKCalpha activity using kemptide as a substrate in presence of 50 uM ATP by mass spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50342213(1-[1-(3-Diethylaminopropyl)-1H-indol-3-yl]-3-(6-ph...)
Affinity DataIC50:  2.69E+3nMAssay Description:Inhibition of human PKCalpha activity using kemptide as a substrate in presence of 50 uM ATP by mass spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50342214(1-[1-(3-Diethylaminopropyl)-1H-indol-3-yl]-3-(2-ph...)
Affinity DataIC50:  4.81E+3nMAssay Description:Inhibition of human PKCalpha activity using kemptide as a substrate in presence of 50 uM ATP by mass spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C alpha type(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50342215(1-[1-(3-Diethylaminopropyl)-1H-indol-3-yl]-3-(6-ph...)
Affinity DataIC50:  8.07E+3nMAssay Description:Inhibition of human PKCalpha activity using kemptide as a substrate in presence of 50 uM ATP by mass spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetcAMP-dependent protein kinase catalytic subunit beta(Homo sapiens (Human))
Procter & Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50342212(1-[1-(3-Dimethylaminopropyl)-1H-indol-3-yl]-3-(4-p...)
Affinity DataIC50:  2.36E+4nMAssay Description:Inhibition of PKA activity using neurogranin as a substrate in presence of 50 uM ATP by mass spectrometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed