Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 4638
TargetTyrosine-protein kinase JAK2(Human)
University of Luxembourg

LigandPNGBDBM26198(Jak Inhibitor 1 | CHEMBL21156 | Compound # 2 | 4-t...)
Affinity DataIC50: 4.5nMpH: 7.5 T: 2°CAssay Description:Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
University of Luxembourg

LigandPNGBDBM26198(Jak Inhibitor 1 | CHEMBL21156 | Compound # 2 | 4-t...)
Affinity DataIC50: 5.20nMpH: 7.5 T: 2°CAssay Description:Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
University of Luxembourg

LigandPNGBDBM81442(CP-690,550)
Affinity DataIC50: 6.10nMpH: 7.5 T: 2°CAssay Description:Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2011
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
University of Luxembourg

LigandPNGBDBM26198(Jak Inhibitor 1 | CHEMBL21156 | Compound # 2 | 4-t...)
Affinity DataIC50: 7nMpH: 7.5 T: 2°CAssay Description:Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
University of Luxembourg

LigandPNGBDBM81442(CP-690,550)
Affinity DataIC50: 8nMpH: 7.5 T: 2°CAssay Description:Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
University of Luxembourg

LigandPNGBDBM50335231(NIBR3049 | CHEMBL1650951 | 3-{5-[4-(2-Hydroxy-2-me...)
Affinity DataIC50: 8nMpH: 7.5 T: 2°CAssay Description:Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
University of Luxembourg

LigandPNGBDBM81442(CP-690,550)
Affinity DataIC50: 12nMpH: 7.5 T: 2°CAssay Description:Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
University of Luxembourg

LigandPNGBDBM26198(Jak Inhibitor 1 | CHEMBL21156 | Compound # 2 | 4-t...)
Affinity DataIC50: 41nMpH: 7.5 T: 2°CAssay Description:Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2011
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
University of Luxembourg

LigandPNGBDBM81442(CP-690,550)
Affinity DataIC50: 176nMpH: 7.5 T: 2°CAssay Description:Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
University of Luxembourg

LigandPNGBDBM50335231(NIBR3049 | CHEMBL1650951 | 3-{5-[4-(2-Hydroxy-2-me...)
Affinity DataIC50: 1.02E+3nMpH: 7.5 T: 2°CAssay Description:Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2011
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
University of Luxembourg

LigandPNGBDBM50335231(NIBR3049 | CHEMBL1650951 | 3-{5-[4-(2-Hydroxy-2-me...)
Affinity DataIC50: 2.55E+3nMpH: 7.5 T: 2°CAssay Description:Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2011
Entry Details Article
PubMed
TargetNon-receptor tyrosine-protein kinase TYK2(Human)
University of Luxembourg

LigandPNGBDBM50335231(NIBR3049 | CHEMBL1650951 | 3-{5-[4-(2-Hydroxy-2-me...)
Affinity DataIC50: 8.06E+3nMpH: 7.5 T: 2°CAssay Description:Enzyme assay affinity-purified GST fusions of the active kinase domains (GST-Jak1(866-1154), GST-Jak2(808-1132), GST-Jak3(811-1124) and GST-Tyk2(888-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/19/2011
Entry Details Article
PubMed