Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50033397
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344532BDBM50344532(4-(2-(3-tert-butylphenylamino)benzo[d]thiazol-5-yl...)
Affinity DataIC50: 1nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344525BDBM50344525(4-(2-(3-tert-butylphenylamino)benzo[d]thiazol-5-yl...)
Affinity DataIC50: 1nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344541BDBM50344541(4-(2-(4-ethylphenylamino)benzo[d]oxazol-5-yloxy)-N...)
Affinity DataIC50: 1nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344540BDBM50344540(4-(2-(4-isopropylphenylamino)benzo[d]oxazol-5-ylox...)
Affinity DataIC50: 1nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344548BDBM50344548(4-(2-(3-tert-butyl phenylamino)benzo[d]oxazol-5-yl...)
Affinity DataIC50: 1nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344530BDBM50344530(4-(2-(4-bromophenylamino)benzo[d]thiazol-5-yloxy)-...)
Affinity DataIC50: 2nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344538BDBM50344538(N-methyl-4-(2-(4-(trifluoromethoxy)phenylamino)ben...)
Affinity DataIC50: 2nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344539BDBM50344539(4-(2-(4-butylphenylamino)benzo[d]oxazol-5-yloxy)-N...)
Affinity DataIC50: 2nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344542BDBM50344542(4-(2-(4-bromophenylamino)benzo[d]oxazol-5-yloxy)-N...)
Affinity DataIC50: 3nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344527BDBM50344527(4-(2-(4-isopropylphenylamino)benzo[d]thiazol-5-ylo...)
Affinity DataIC50: 3nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344543BDBM50344543(4-(2-(3-isopropylphenylamino)benzo[d]oxazol-5-ylox...)
Affinity DataIC50: 3nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344531BDBM50344531(4-(2-(4-chlorophenylamino)benzo[d]thiazol-5-yloxy)...)
Affinity DataIC50: 4nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344526BDBM50344526(N-methyl-4-(2-(4-(trifluoromethoxy)phenylamino)ben...)
Affinity DataIC50: 4nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344534BDBM50344534(4-(2-(3-isopropylphenylamino)benzo[d]oxazol-5-ylox...)
Affinity DataIC50: 4nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344529BDBM50344529(N-methyl-4-(2-(p-tolylamino)benzo[d]thiazol-5-ylox...)
Affinity DataIC50: 7nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344528BDBM50344528(4-(2-(4-butylphenylamino)benzo[d]thiazol-5-yloxy)-...)
Affinity DataIC50: 9nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344536BDBM50344536(4-(2-(4-(dimethylamino)phenylamino)benzo[d]oxazol-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 17696BDBM17696(4-({2-[(4-chlorophenyl)amino]-1,3-benzoxazol-5-yl}...)
Affinity DataIC50: 19nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344544BDBM50344544(N-methyl-4-(2-(3-(trifluoromethyl)phenylamino)benz...)
Affinity DataIC50: 27nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344524BDBM50344524(4-(2-(4-bromophenylamino)benzo[d]thiazol-5-yloxy)-...)
Affinity DataIC50: 41nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344537BDBM50344537(N-methyl-4-(2-(4-phenoxyphenylamino)benzo[d]oxazol...)
Affinity DataIC50: 53nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344545BDBM50344545(4-(2-(2-ethylphenylamino)benzo[d]oxazol-5-yloxy)-N...)
Affinity DataIC50: 110nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344546BDBM50344546(4-(2-(2-chlorophenylamino)benzo[d]oxazol-5-yloxy)-...)
Affinity DataIC50: 120nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344533BDBM50344533(4-(2-(3-isopropylphenylamino)benzo[d]oxazol-5-ylox...)
Affinity DataIC50: 140nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344547BDBM50344547(4-(2-(2-fluorophenylamino)benzo[d]oxazol-5-yloxy)-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50344535BDBM50344535(4-(2-(4-(4-ethylpiperazin-1-yl)phenylamino)benzo[d...)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of c-Raf assessed as phosphorylation of MEK1/2 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/4/2011
Entry Details Article
PubMed