Compile Data Set for Download or QSAR
maximum 50k data
Found 44 Enz. Inhib. hit(s) with all data for entry = 50033835
TargetCytochrome P450 2C9(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352206(CHEMBL1825089)
Affinity DataIC50:  1nMAssay Description:Inhibition of CYP2C9 using a fluorescent probe 7-methoxy-4-trifluoromethylcoumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352202(CHEMBL1825101)
Affinity DataIC50:  3nMAssay Description:Inhibition of CDK1/Cyclin B assessed as phosphorylation of Z-lyte Peptide at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352200(CHEMBL1825100)
Affinity DataIC50:  4nMAssay Description:Inhibition of CDK1/Cyclin B assessed as phosphorylation of Z-lyte Peptide at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352209(CHEMBL1825092)
Affinity DataIC50:  5nMAssay Description:Inhibition of Aurora kinase A assessed as phosphorylation of Lats2 substrate at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352208(CHEMBL1825090)
Affinity DataIC50:  5nMAssay Description:Inhibition of Aurora kinase A assessed as phosphorylation of Lats2 substrate at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352208(CHEMBL1825090)
Affinity DataIC50:  5nMAssay Description:Inhibition of CDK1/Cyclin B assessed as phosphorylation of Z-lyte Peptide at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352212(CHEMBL1821761)
Affinity DataIC50:  5nMAssay Description:Inhibition of CDK1/Cyclin B assessed as phosphorylation of Z-lyte Peptide at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352215(CHEMBL1825093)
Affinity DataIC50:  5nMAssay Description:Inhibition of CDK1/Cyclin B assessed as phosphorylation of Z-lyte Peptide at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352210(CHEMBL1825091)
Affinity DataIC50:  6nMAssay Description:Inhibition of CDK1/Cyclin B assessed as phosphorylation of Z-lyte Peptide at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352210(CHEMBL1825091)
Affinity DataIC50:  6nMAssay Description:Inhibition of Aurora kinase A assessed as phosphorylation of Lats2 substrate at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352211(CHEMBL1825095)
Affinity DataIC50:  6nMAssay Description:Inhibition of CDK1/Cyclin B assessed as phosphorylation of Z-lyte Peptide at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352205(CHEMBL1825096)
Affinity DataIC50:  7nMAssay Description:Inhibition of CDK1/Cyclin B assessed as phosphorylation of Z-lyte Peptide at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352211(CHEMBL1825095)
Affinity DataIC50:  9nMAssay Description:Inhibition of Aurora kinase A assessed as phosphorylation of Lats2 substrate at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352203(CHEMBL1825099)
Affinity DataIC50:  10nMAssay Description:Inhibition of CDK1/Cyclin B assessed as phosphorylation of Z-lyte Peptide at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352204(CHEMBL1825098)
Affinity DataIC50:  10nMAssay Description:Inhibition of CDK1/Cyclin B assessed as phosphorylation of Z-lyte Peptide at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352214(CHEMBL1825102)
Affinity DataIC50:  13nMAssay Description:Inhibition of CDK1/Cyclin B assessed as phosphorylation of Z-lyte Peptide at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352212(CHEMBL1821761)
Affinity DataIC50:  13nMAssay Description:Inhibition of Aurora kinase A assessed as phosphorylation of Lats2 substrate at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352206(CHEMBL1825089)
Affinity DataIC50:  14nMAssay Description:Inhibition of Aurora kinase A assessed as phosphorylation of Lats2 substrate at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352205(CHEMBL1825096)
Affinity DataIC50:  17nMAssay Description:Inhibition of Aurora kinase A assessed as phosphorylation of Lats2 substrate at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352215(CHEMBL1825093)
Affinity DataIC50:  20nMAssay Description:Inhibition of Aurora kinase A assessed as phosphorylation of Lats2 substrate at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352206(CHEMBL1825089)
Affinity DataIC50:  23nMAssay Description:Inhibition of CDK1/Cyclin B assessed as phosphorylation of Z-lyte Peptide at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352213(CHEMBL1825094)
Affinity DataIC50:  23nMAssay Description:Inhibition of CDK1/Cyclin B assessed as phosphorylation of Z-lyte Peptide at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352206(CHEMBL1825089)
Affinity DataIC50:  30nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352213(CHEMBL1825094)
Affinity DataIC50:  30nMAssay Description:Inhibition of Aurora kinase A assessed as phosphorylation of Lats2 substrate at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352201(CHEMBL1825097)
Affinity DataIC50:  31nMAssay Description:Inhibition of CDK1/Cyclin B assessed as phosphorylation of Z-lyte Peptide at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352206(CHEMBL1825089)
Affinity DataIC50:  40nMAssay Description:Inhibition of CYP3A4 using a fluorescent probe 7-benzyloxyquinolineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352206(CHEMBL1825089)
Affinity DataIC50:  40nMAssay Description:Inhibition of CYP3A4 using a fluorescent probe 7-benzyloxy-4(trifluoromethyl)-coumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352209(CHEMBL1825092)
Affinity DataIC50:  90nMAssay Description:Inhibition of CDK1/Cyclin B assessed as phosphorylation of Z-lyte Peptide at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352214(CHEMBL1825102)
Affinity DataIC50:  95nMAssay Description:Inhibition of Aurora kinase A assessed as phosphorylation of Lats2 substrate at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352200(CHEMBL1825100)
Affinity DataIC50:  110nMAssay Description:Inhibition of Aurora kinase A assessed as phosphorylation of Lats2 substrate at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352201(CHEMBL1825097)
Affinity DataIC50:  150nMAssay Description:Inhibition of Aurora kinase A assessed as phosphorylation of Lats2 substrate at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352202(CHEMBL1825101)
Affinity DataIC50:  180nMAssay Description:Inhibition of Aurora kinase A assessed as phosphorylation of Lats2 substrate at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
TargetAurora kinase A(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352203(CHEMBL1825099)
Affinity DataIC50:  260nMAssay Description:Inhibition of Aurora kinase A assessed as phosphorylation of Lats2 substrate at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352204(CHEMBL1825098)
Affinity DataIC50:  350nMAssay Description:Inhibition of Aurora kinase A assessed as phosphorylation of Lats2 substrate at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352205(CHEMBL1825096)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 using a fluorescent probe 7-benzyloxy-4(trifluoromethyl)-coumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352205(CHEMBL1825096)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP3A4 using a fluorescent probe 7-benzyloxyquinolineMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352205(CHEMBL1825096)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352205(CHEMBL1825096)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2C9 using a fluorescent probe 7-methoxy-4-trifluoromethylcoumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352206(CHEMBL1825089)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 using a fluorescent probe 3-[2-(N,N-diethyl-N-methylamino)ethyl]-7-methoxy-4methylcoumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase/G2/mitotic-specific cyclin- 1(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352207(CHEMBL1825103)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CDK1/Cyclin B assessed as phosphorylation of Z-lyte Peptide at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352205(CHEMBL1825096)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP2D6 using a fluorescent probe 3-[2-(N,N-diethyl-N-methylamino)ethyl]-7-methoxy-4methylcoumarinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352207(CHEMBL1825103)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of Aurora kinase A assessed as phosphorylation of Lats2 substrate at 0.017 to 30 nM by FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352205(CHEMBL1825096)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Biogen Idec

Curated by ChEMBL
LigandPNGBDBM50352206(CHEMBL1825089)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed