Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50034050
TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50356004(CHEMBL1911339)
Affinity DataIC50: 0.0600nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50356003(CHEMBL1911338)
Affinity DataIC50: 0.160nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50356002(CHEMBL1911337)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355999(CHEMBL1911334)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50356007(CHEMBL1911342)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355997(CHEMBL1911332 | US8772288, 63)
Affinity DataIC50: 2nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50356001(CHEMBL1911336)
Affinity DataIC50: 4nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355998(CHEMBL1911333 | US8772288, 67)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50356006(CHEMBL1911341)
Affinity DataIC50: 5nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355989(CHEMBL1911193 | US8772288, 53)
Affinity DataIC50: 7.40nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355990(CHEMBL1911194 | US8772288, 59)
Affinity DataIC50: 7.60nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355993(CHEMBL1911197)
Affinity DataIC50: 9nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355995(CHEMBL1909657 | US8772288, 54)
Affinity DataIC50: 18nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355986(CHEMBL1911190 | US8772288, 70)
Affinity DataIC50: 32nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50356008(CHEMBL1911344)
Affinity DataIC50: 34nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50356005(CHEMBL1911340)
Affinity DataIC50: 38nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50356000(CHEMBL1911335)
Affinity DataIC50: 38nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355996(CHEMBL1911331)
Affinity DataIC50: 87nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355994(CHEMBL1911198)
Affinity DataIC50: 135nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355991(CHEMBL1911195)
Affinity DataIC50: 173nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355987(CHEMBL1911191)
Affinity DataIC50: 583nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355988(CHEMBL1911192)
Affinity DataIC50: 741nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355992(CHEMBL1911196)
Affinity DataIC50: 880nMAssay Description:Inhibition of human p38alpha using biotinylated ATF2 as substrate preincubated for 1 hr measured after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetRAF proto-oncogene serine/threonine-protein kinase(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355990(CHEMBL1911194 | US8772288, 59)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of cRafMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355990(CHEMBL1911194 | US8772288, 59)
Affinity DataIC50: 7.70E+3nMAssay Description:Inhibition of human TrkAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1B(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355990(CHEMBL1911194 | US8772288, 59)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 5-HT1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355990(CHEMBL1911194 | US8772288, 59)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355990(CHEMBL1911194 | US8772288, 59)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355990(CHEMBL1911194 | US8772288, 59)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355990(CHEMBL1911194 | US8772288, 59)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50355990(CHEMBL1911194 | US8772288, 59)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/20/2012
Entry Details Article
PubMed