Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 5633
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
University of North Carolina

LigandPNGBDBM86219(CAS_5537 | NSC_5537 | Trequinsin)
Affinity DataIC50: 0.300nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of North Carolina

LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of North Carolina

LigandPNGBDBM92338(Wyq16#)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
University of North Carolina

LigandPNGBDBM15297(N-Cyclohexyl-N-methyl-4-(2-oxo-1,2-dihydro-quinoli...)
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM92338(Wyq16#)
Affinity DataIC50: 230nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
University of North Carolina

LigandPNGBDBM15296(Milrinone | CHEMBL189 | 6-methyl-2-oxo-5-pyridin-4...)
Affinity DataIC50: 300nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMed
LigandPNGBDBM23620(Dipyridamine | SMR000058382 | MLS000028420 | CHEMB...)
Affinity DataIC50: 500nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of North Carolina

LigandPNGBDBM23620(Dipyridamine | SMR000058382 | MLS000028420 | CHEMB...)
Affinity DataIC50: 500nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
University of North Carolina

LigandPNGBDBM14769(6-[4-(difluoromethoxy)-3-methoxyphenyl]-2,3-dihydr...)
Affinity DataIC50: 500nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
University of North Carolina

LigandPNGBDBM14769(6-[4-(difluoromethoxy)-3-methoxyphenyl]-2,3-dihydr...)
Affinity DataIC50: 500nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM50020875(1-Ethyl-4-(N'-isopropylidene-hydrazino)-1H-pyrazol...)
Affinity DataIC50: 700nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Human)
University of North Carolina

LigandPNGBDBM22926(3-(6-amino-9H-purin-9-yl)nonan-2-ol | Erythro-9-(2...)
Affinity DataIC50: 800nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 1.00E+3nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
University of North Carolina

LigandPNGBDBM50020875(1-Ethyl-4-(N'-isopropylidene-hydrazino)-1H-pyrazol...)
Affinity DataIC50: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
University of North Carolina

LigandPNGBDBM92337(Ro20-1724)
Affinity DataIC50: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
University of North Carolina

LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 2.00E+3nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM86219(CAS_5537 | NSC_5537 | Trequinsin)
Affinity DataIC50: 3.90E+3nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM23620(Dipyridamine | SMR000058382 | MLS000028420 | CHEMB...)
Affinity DataIC50: 6.90E+3nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM14754(CHEMBL19224 | 1-[(3,4-dimethoxyphenyl)methyl]-6,7-...)
Affinity DataIC50: 2.50E+4nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM15336(1-methyl-3-(2-methylpropyl)-2,3,6,7-tetrahydro-1H-...)
Affinity DataIC50: 6.80E+4nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM10850(1-(5-Oxohexyl)theobromine (pentoxifylline) | 3,7-d...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM92337(Ro20-1724)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM14361(Adeo | 4-(3-cyclopentyloxy-4-methoxy-phenyl)pyrrol...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM14769(6-[4-(difluoromethoxy)-3-methoxyphenyl]-2,3-dihydr...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM15297(N-Cyclohexyl-N-methyl-4-(2-oxo-1,2-dihydro-quinoli...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM15296(Milrinone | CHEMBL189 | 6-methyl-2-oxo-5-pyridin-4...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMed
TargetPhosphodiesterase(Trypanosoma cruzi)
University of North Carolina

LigandPNGBDBM22926(3-(6-amino-9H-purin-9-yl)nonan-2-ol | Erythro-9-(2...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:Enzymatic activities were assayed using [3H] cAMP and [3H]cGMP as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2012
Entry Details Article
PubMed