Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50040560
TargetTelomerase reverse transcriptase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50107609(CHEMBL2170855 | CHEMBL337559 | TMPyP4 | 5,10,15,20...)
Affinity DataIC50: 60nMAssay Description:Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction by te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50126186(2-(3-Naphthalen-2-yl-but-2-enoylamino)-benzoic aci...)
Affinity DataIC50: 93nMAssay Description:Inhibition of telomerase in human HeLa cells after 2 hrs by [alpha-32P]dGTP incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50107609(CHEMBL2170855 | CHEMBL337559 | TMPyP4 | 5,10,15,20...)
Affinity DataIC50: 147nMAssay Description:Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50157547(7,8,3',4'-tetrahydroxyflavone | 2-(3,4-dihydroxyph...)
Affinity DataIC50: 200nMAssay Description:Inhibition of telomerase in human HEK293 cells by flashplate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50157547(7,8,3',4'-tetrahydroxyflavone | 2-(3,4-dihydroxyph...)
Affinity DataIC50: 230nMAssay Description:Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction by te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50157547(7,8,3',4'-tetrahydroxyflavone | 2-(3,4-dihydroxyph...)
Affinity DataIC50: 250nMAssay Description:Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50396097(CHEMBL2170856)
Affinity DataIC50: 670nMAssay Description:Inhibition of telomerase in human U937 cells by telomeric repeat amplification protocolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin-3-o-gallate | (-)-Epigallocat...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of telomerase in human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin-3-o-gallate | (-)-Epigallocat...)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50070942((-)-Epigallocatechin-3-o-gallate | (-)-Epigallocat...)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction by te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50396098(CHEMBL2170857)
Affinity DataIC50: 1.32E+3nMAssay Description:Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction by te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50396098(CHEMBL2170857)
Affinity DataIC50: 1.53E+3nMAssay Description:Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50396098(CHEMBL2170857)
Affinity DataIC50: 3.06E+3nMAssay Description:Inhibition of telomerase in human K562 cells by modified telomeric repeat amplification protocolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50126186(2-(3-Naphthalen-2-yl-but-2-enoylamino)-benzoic aci...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction by te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50126186(2-(3-Naphthalen-2-yl-but-2-enoylamino)-benzoic aci...)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50396097(CHEMBL2170856)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction by te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50396097(CHEMBL2170856)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed