Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50040492
TargetNeuropeptide FF receptor 1(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM86143(RFamide-related peptide 3 | L-Val-L-Pro-L-Asn-L-Le...)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human NPFF1 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM86143(RFamide-related peptide 3 | L-Val-L-Pro-L-Asn-L-Le...)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at human NPFF2 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 1(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50060728((R)-5-(diaminomethyleneamino)-2-(2,2-diphenylaceta...)
Affinity DataKd:  20.9nMAssay Description:Competitive antagonist activity at human NPFF1 receptor expressed in COS1 cells assessed as inhibition of NPVF-induced [3H]inositol phosphate accumul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 1(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50394976(CHEMBL2165922)
Affinity DataKd:  41.7nMAssay Description:Competitive antagonist activity at human NPFF1 receptor expressed in COS1 cells assessed as inhibition of NPVF-induced [3H]inositol phosphate accumul...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 1(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50336912(Adamantane-1-carboxylic acid [(S)-1-((S)-1-carbamo...)
Affinity DataEC50:  71nMAssay Description:Agonist activity at human NPFF1 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50060728((R)-5-(diaminomethyleneamino)-2-(2,2-diphenylaceta...)
Affinity DataEC50:  233nMAssay Description:Agonist activity at human NPFF2 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50394976(CHEMBL2165922)
Affinity DataEC50:  298nMAssay Description:Agonist activity at human NPFF2 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50336912(Adamantane-1-carboxylic acid [(S)-1-((S)-1-carbamo...)
Affinity DataEC50:  379nMAssay Description:Agonist activity at human NPFF2 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 1(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50394978(CHEMBL573297)
Affinity DataEC50:  527nMAssay Description:Agonist activity at human NPFF1 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50394977(CHEMBL583068)
Affinity DataEC50:  1.19E+3nMAssay Description:Agonist activity at human NPFF2 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50394975(CHEMBL2165921)
Affinity DataEC50:  1.66E+3nMAssay Description:Agonist activity at human NPFF2 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 2(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50394978(CHEMBL573297)
Affinity DataEC50:  2.20E+3nMAssay Description:Agonist activity at human NPFF2 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 1(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50394977(CHEMBL583068)
Affinity DataEC50:  2.37E+3nMAssay Description:Agonist activity at human NPFF1 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuropeptide FF receptor 1(Human)
Leipzig University

Curated by ChEMBL
LigandPNGBDBM50394975(CHEMBL2165921)
Affinity DataEC50:  5.62E+3nMAssay Description:Agonist activity at human NPFF1 receptor expressed in COS1 cells assessed as [3H]inositol phosphate accumulation after 2 hrs by liquid scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed