Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50042135
TargetSonic hedgehog protein(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421186(CHEMBL2086800)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50401328(CHEMBL2087239)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421184(CHEMBL2086798)
Affinity DataIC50: 5.10nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421190(CHEMBL2086805)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421187(CHEMBL2086801)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421193(CHEMBL2086802)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421189(CHEMBL2086804)
Affinity DataIC50: 21nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421188(CHEMBL2086803)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421191(CHEMBL2086402)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421192(CHEMBL2087240)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetSonic hedgehog protein(Mouse)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50421185(CHEMBL2086799)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of recombinant mouse Shh expressed in human NIH/3T3 cells assessed as inhibition of Gli1 expression after 48 hrs by luciferase reporter ge...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed