Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50040678
TargetBromodomain-containing protein 4(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataKd:  49nMAssay Description:Binding affinity to BRD4 isoform 1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50365262(CHEMBL1957266 | (S)-JQ1 (1) | US9320741, (S)-JQ1 |...)
Affinity DataIC50: 77nMAssay Description:Displacement of H4(1-21)KAc5,8,12,16 peptide from BRD4 isoform 1 bead based amplified luminescent proximity homogeneous assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT2B(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50398244(CHEMBL609728)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of biotinylated Tat-KAc50 peptide binding to PCAFMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 2(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50365462(CHEMBL1738777)
Affinity DataKd:  2.80E+4nMAssay Description:Binding affinity to BRD2 isoform 1 by SPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed