Compile Data Set for Download or QSAR
maximum 50k data
Found 38 Enz. Inhib. hit(s) with all data for entry = 50042798
TargetPlasma kallikrein(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431213(CHEMBL2332604)
Affinity DataKi:  0.300nMAssay Description:Inhibition of human recombinant polyhistidine-tagged plasma kallikrein expressed in Escherichia coli XL1 blue using Z-FR-AMC as substrate by fluorime...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431213(CHEMBL2332604)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human biotinylated beta factor 12a expressed in Escherichia coli TG1 using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431221(CHEMBL2332614)
Affinity DataKi:  3.10E+3nMAssay Description:Inhibition of human biotinylated beta factor 12a expressed in Escherichia coli TG1 using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431220(CHEMBL2332610)
Affinity DataKi:  3.10E+3nMAssay Description:Inhibition of human biotinylated beta factor 12a expressed in Escherichia coli TG1 using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431222(CHEMBL2332607 | Scsgrrcppsyck)
Affinity DataKi:  3.30E+3nMAssay Description:Inhibition of human plasmin using H-D-Val-Leu-Lys-AMC as substrate assessed as residual activity by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431214(CHEMBL2332603)
Affinity DataKi:  4.30E+3nMAssay Description:Inhibition of human plasmin using H-D-Val-Leu-Lys-AMC as substrate assessed as residual activity by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431215(CHEMBL2332612)
Affinity DataKi:  4.70E+3nMAssay Description:Inhibition of human biotinylated beta factor 12a expressed in Escherichia coli TG1 using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431224(CHEMBL2332613)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of human biotinylated beta factor 12a expressed in Escherichia coli TG1 using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431223(CHEMBL2332615)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of human biotinylated beta factor 12a expressed in Escherichia coli TG1 using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431222(CHEMBL2332607 | Scsgrrcppsyck)
Affinity DataKi:  7.80E+3nMAssay Description:Inhibition of human biotinylated beta factor 12a expressed in Escherichia coli TG1 using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431221(CHEMBL2332614)
Affinity DataKi:  8.30E+3nMAssay Description:Inhibition of human plasmin using H-D-Val-Leu-Lys-AMC as substrate assessed as residual activity by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431220(CHEMBL2332610)
Affinity DataKi:  8.30E+3nMAssay Description:Inhibition of human plasmin using H-D-Val-Leu-Lys-AMC as substrate assessed as residual activity by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431219(CHEMBL2332616)
Affinity DataKi:  1.02E+4nMAssay Description:Inhibition of human biotinylated beta factor 12a expressed in Escherichia coli TG1 using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431218(CHEMBL2332606)
Affinity DataKi:  1.12E+4nMAssay Description:Inhibition of human biotinylated beta factor 12a expressed in Escherichia coli TG1 using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431218(CHEMBL2332606)
Affinity DataKi:  1.42E+4nMAssay Description:Inhibition of human plasmin using H-D-Val-Leu-Lys-AMC as substrate assessed as residual activity by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431217(CHEMBL2332611)
Affinity DataKi:  2.05E+4nMAssay Description:Inhibition of human biotinylated beta factor 12a expressed in Escherichia coli TG1 using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431216(CHEMBL2332605)
Affinity DataKi:  3.35E+4nMAssay Description:Inhibition of human biotinylated beta factor 12a expressed in Escherichia coli TG1 using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431225(CHEMBL2332609)
Affinity DataKi: >7.50E+4nMAssay Description:Inhibition of human biotinylated beta factor 12a expressed in Escherichia coli TG1 using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XII(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431226(CHEMBL2332608)
Affinity DataKi: >7.50E+4nMAssay Description:Inhibition of human biotinylated beta factor 12a expressed in Escherichia coli TG1 using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431215(CHEMBL2332612)
Affinity DataKi:  1.18E+5nMAssay Description:Inhibition of human plasmin using H-D-Val-Leu-Lys-AMC as substrate assessed as residual activity by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431213(CHEMBL2332604)
Affinity DataKi: >1.20E+5nMAssay Description:Inhibition of human PK using Z-Phe-Arg-AMC as substrate assessed as residual activity by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431213(CHEMBL2332604)
Affinity DataKi: >1.20E+5nMAssay Description:Inhibition of human thrombin using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431213(CHEMBL2332604)
Affinity DataKi: >1.20E+5nMAssay Description:Inhibition of human plasmin using H-D-Val-Leu-Lys-AMC as substrate assessed as residual activity by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431213(CHEMBL2332604)
Affinity DataKi: >1.20E+5nMAssay Description:Inhibition of human trypsin using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431220(CHEMBL2332610)
Affinity DataKi: >1.20E+5nMAssay Description:Inhibition of human trypsin using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431216(CHEMBL2332605)
Affinity DataKi: >1.20E+5nMAssay Description:Inhibition of human plasmin using H-D-Val-Leu-Lys-AMC as substrate assessed as residual activity by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431219(CHEMBL2332616)
Affinity DataKi: >1.20E+5nMAssay Description:Inhibition of human plasmin using H-D-Val-Leu-Lys-AMC as substrate assessed as residual activity by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431223(CHEMBL2332615)
Affinity DataKi: >1.20E+5nMAssay Description:Inhibition of human plasmin using H-D-Val-Leu-Lys-AMC as substrate assessed as residual activity by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431224(CHEMBL2332613)
Affinity DataKi: >1.20E+5nMAssay Description:Inhibition of human plasmin using H-D-Val-Leu-Lys-AMC as substrate assessed as residual activity by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431217(CHEMBL2332611)
Affinity DataKi: >1.20E+5nMAssay Description:Inhibition of human plasmin using H-D-Val-Leu-Lys-AMC as substrate assessed as residual activity by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431220(CHEMBL2332610)
Affinity DataKi: >1.20E+5nMAssay Description:Inhibition of human thrombin using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasma kallikrein(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431220(CHEMBL2332610)
Affinity DataKi: >1.20E+5nMAssay Description:Inhibition of human PK using Z-Phe-Arg-AMC as substrate assessed as residual activity by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431220(CHEMBL2332610)
Affinity DataKi: >1.20E+5nMAssay Description:Inhibition of human coagulation factor 11a using Boc-Phe-Ser-Arg-AMC as substrate assessed as residual activity by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431220(CHEMBL2332610)
Affinity DataKi: >1.20E+5nMAssay Description:Inhibition of human uPA using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431220(CHEMBL2332610)
Affinity DataKi: >1.20E+5nMAssay Description:Inhibition of human tPA using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTissue-type plasminogen activator(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431213(CHEMBL2332604)
Affinity DataKi: >1.20E+5nMAssay Description:Inhibition of human tPA using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetUrokinase-type plasminogen activator(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431213(CHEMBL2332604)
Affinity DataKi: >1.20E+5nMAssay Description:Inhibition of human uPA using Z-Gly-Gly-Arg-AMC as substrate assessed as residual activity by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor XI(Homo sapiens (Human))
Ecole Polytechnique F�D�Rale De Lausanne Epfl

Curated by ChEMBL
LigandPNGBDBM50431213(CHEMBL2332604)
Affinity DataKi: >1.20E+5nMAssay Description:Inhibition of human coagulation factor 11a using Boc-Phe-Ser-Arg-AMC as substrate assessed as residual activity by fluorometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed