Compile Data Set for Download or QSAR
Report error Found 32 Enz. Inhib. hit(s) with all data for entry = 50043375
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132450BDBM50132450(3-[1-(5-Methoxy-1-methyl-1H-indol-3-yl)-meth-(Z)-y...)
Affinity DataIC50: 5nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126413BDBM50126413(N*1*-[7-(4-Morpholin-4-yl-phenyl)-[1,6]naphthyridi...)
Affinity DataIC50: 8nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249285BDBM50249285(2-(2-aminoethylamino)-4-(3-bromophenylamino)pyrimi...)
Affinity DataIC50: 23nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249287BDBM50249287(2-(2-aminoethylamino)-4-(m-tolylamino)pyrimidine-5...)
Affinity DataIC50: 30nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249319BDBM50249319(CHEMBL471901 | 2-(2-aminoethylamino)-4-(3-(trifluo...)
Affinity DataIC50: 41nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249354BDBM50249354(2-(4-aminobutylamino)-4-(3-(trifluoromethyl)phenyl...)
Affinity DataIC50: 47nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126410BDBM50126410(N1-(7-(4-(dimethylamino)phenyl)-1,6-naphthyridin-5...)
Affinity DataIC50: 72nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126440BDBM50126440(N-[7-(4-Dimethylamino-phenyl)-[1,6]naphthyridin-5-...)
Affinity DataIC50: 78nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126438BDBM50126438(N*1*-[3-Bromo-7-(4-methoxy-phenyl)-[1,6]naphthyrid...)
Affinity DataIC50: 120nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249452BDBM50249452(2-(2-aminoethylamino)-4-(p-tolylamino)pyrimidine-5...)
Affinity DataIC50: 150nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126436BDBM50126436({4-[5-(4-Amino-butoxy)-[1,6]naphthyridin-7-yl]-phe...)
Affinity DataIC50: 160nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126431BDBM50126431(3-(7-(4-(dimethylamino)phenyl)-1,6-naphthyridin-5-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126423BDBM50126423(4-[7-(4-Dimethylamino-phenyl)-[1,6]naphthyridin-5-...)
Affinity DataIC50: 200nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126433BDBM50126433(N*1*-[7-(4-Dimethylamino-phenyl)-[1,6]naphthyridin...)
Affinity DataIC50: 210nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249089BDBM50249089(2-(2-aminoethylamino)-4-(o-tolylamino)pyrimidine-5...)
Affinity DataIC50: 230nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126429BDBM50126429(N1-(7-phenyl-1,6-naphthyridin-5-yl)propane-1,3-dia...)
Affinity DataIC50: 410nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126403BDBM50126403(N*1*-(7-{4-[(3-Dimethylamino-propyl)-methyl-amino]...)
Affinity DataIC50: 420nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249212BDBM50249212(2-(2-(dimethylamino)ethylamino)-4-(3-(trifluoromet...)
Affinity DataIC50: 750nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126412BDBM50126412(N-[7-(4-Dimethylamino-phenyl)-[1,6]naphthyridin-5-...)
Affinity DataIC50: 890nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126445BDBM50126445(N*1*-[7-(4'-Methyl-biphenyl-4-yl)-[1,6]naphthyridi...)
Affinity DataIC50: 900nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440116BDBM50440116(CHEMBL2426223)
Affinity DataIC50: 937nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126401BDBM50126401(N*1*-[7-(3-Thiophen-3-yl-phenyl)-[1,6]naphthyridin...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126425BDBM50126425(N-[7-(4-Dimethylamino-phenyl)-[1,6]naphthyridin-5-...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126398BDBM50126398(N*1*-[7-(4-Methoxy-phenyl)-3-phenyl-[1,6]naphthyri...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50132442BDBM50132442(3-(5-Methoxy-1-methyl-1H-indol-3-ylmethyl)-2-oxo-2...)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126435BDBM50126435(N-[7-(4-Dimethylamino-phenyl)-[1,6]naphthyridin-5-...)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440117BDBM50440117(CHEMBL2426222)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440118BDBM50440118(CHEMBL2426221)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50249422BDBM50249422(2-((2-(dimethylamino)ethyl)(methyl)amino)-4-(3-(tr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50440119BDBM50440119(CHEMBL2426220)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50045936BDBM50045936(CHEMBL69863 | 4-(3,5-dihydroxystyryl)benzene-1,2-d...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Punjabi University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50126407BDBM50126407(N*1*-[7-(2-Bromo-phenyl)-[1,6]naphthyridin-5-yl]-p...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of spleen tyrosine kinase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed