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Found 34 Enz. Inhib. hit(s) with all data for entry = 50043664
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50102295(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at recombinant mouse P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM86478(A-317491)
Affinity DataIC50:  35nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(RAT)
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50102295(4-(4-Formyl-5-hydroxy-6-methyl-3-phosphonooxymethy...)
Affinity DataIC50:  43nMAssay Description:Antagonist activity at recombinant rat P2X1 receptor expressed in Xenopus oocytes assessed as ion flux stimulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444434(CHEMBL3091630)
Affinity DataIC50:  60nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM86478(A-317491)
Affinity DataIC50:  97nMAssay Description:Antagonist activity at recombinant human P2X3 receptor transfected in human 1321N1 cells assessed as inhibition of alpha, beta me-ATP-induced current...More data for this Ligand-Target Pair
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)
Affinity DataIC50:  99nMAssay Description:Antagonist activity at mouse P2X1 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444431(CHEMBL3091628)
Affinity DataIC50:  145nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50087267((1-(N,O-bis(1,5-isoquinolinesulfonyl)-N-methyl-L-t...)
Affinity DataIC50:  158nMAssay Description:Antagonist activity at human P2X7 receptor expressed in HEK293 cells assessed as inhibition of BzATP-induced accumulation of ethidium+ after 120 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50087267((1-(N,O-bis(1,5-isoquinolinesulfonyl)-N-methyl-L-t...)
Affinity DataIC50:  210nMAssay Description:Antagonist activity at recombinant human P2X7 receptor assessed as inhibition of BzATP-mediated Yo-Pro uptake measured for 1 hr by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)
Affinity DataIC50:  240nMAssay Description:Antagonist activity at human P2X3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444432(CHEMBL3091610)
Affinity DataIC50:  267nMAssay Description:Antagonist activity at recombinant mouse P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444427(CHEMBL3091631)
Affinity DataIC50:  366nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444433(CHEMBL3091632)
Affinity DataIC50:  377nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444425(CHEMBL3091607)
Affinity DataIC50:  446nMAssay Description:Antagonist activity at recombinant mouse P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444432(CHEMBL3091610)
Affinity DataIC50:  458nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444425(CHEMBL3091607)
Affinity DataIC50:  460nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444435(CHEMBL3091619)
Affinity DataIC50:  474nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444429(CHEMBL3091620)
Affinity DataIC50:  587nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444421(CHEMBL3091629)
Affinity DataIC50:  636nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444424(CHEMBL3091633)
Affinity DataIC50:  638nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444420(CHEMBL3091605)
Affinity DataIC50:  645nMAssay Description:Antagonist activity at recombinant mouse P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444428(CHEMBL3091635)
Affinity DataIC50:  652nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444419(CHEMBL3091625)
Affinity DataIC50:  723nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 1(Mus musculus)
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444418(CHEMBL3091606)
Affinity DataIC50:  768nMAssay Description:Antagonist activity at recombinant mouse P2X1 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444420(CHEMBL3091605)
Affinity DataIC50:  797nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444426(CHEMBL3091618)
Affinity DataIC50:  824nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444423(CHEMBL3091634)
Affinity DataIC50:  856nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444418(CHEMBL3091606)
Affinity DataIC50:  920nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444422(CHEMBL3091627)
Affinity DataIC50:  928nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444417(CHEMBL3091622)
Affinity DataIC50:  1.05E+3nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 7(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM85043(CAS_149017-66-3 | CHEMBL69234 | NSC_6093163 | PPAD...)
Affinity DataIC50:  1.18E+3nMAssay Description:Antagonist activity at recombinant human P2X7 receptor assessed as inhibition of BzATP-mediated Yo-Pro uptake measured for 1 hr by FLIPR assayMore data for this Ligand-Target Pair
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444430(CHEMBL3091617)
Affinity DataIC50:  1.25E+3nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444416(CHEMBL3091623)
Affinity DataIC50:  2.93E+3nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetP2X purinoceptor 3(Homo sapiens (Human))
Gwangju Institute Of Science And Technology (Gist)

Curated by ChEMBL
LigandPNGBDBM50444415(CHEMBL3091621)
Affinity DataIC50:  3.30E+3nMAssay Description:Antagonist activity at recombinant human P2X3 receptor expressed in Xenopus oocytes assessed as inhibition of ATP-induced ion current preincubated fo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed