Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of rat recombinant GluN1/GluN2D expressed in Xenopus laevis oocytes assessed as reduction in current responseMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2B(Rattus norvegicus (Rat))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of rat recombinant GluN1/GluN2B expressed in Xenopus laevis oocytes assessed as reduction in current responseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as reduction in current responseMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, NMDA 1/2A(Rattus norvegicus (Rat))
Emory University
Curated by ChEMBL
Emory University
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of rat recombinant GluN1/GluN2A expressed in Xenopus laevis oocytes assessed as reduction in current responseMore data for this Ligand-Target Pair
Affinity DataEC50: 7.00E+3nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 1.60E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 8.70E+3nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 1.10E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 8.90E+3nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 1.50E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 1.60E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 2.90E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 1.50E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 4.60E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 3.50E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 3.60E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 3.70E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 1.60E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 1.30E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 8.50E+3nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 4.30E+3nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 8.00E+3nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 1.80E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 7.00E+3nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 2.50E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 8.20E+3nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 9.70E+3nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 1.30E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 1.30E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 4.00E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 3.70E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 5.20E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 1.40E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 1.05E+5nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 1.60E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 1.70E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 5.20E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 6.10E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 2.40E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair
Affinity DataEC50: 2.40E+4nMAssay Description:Potentiation of rat recombinant GluN1/GluN2C expressed in Xenopus laevis oocytes assessed as increase in glutamate/glycine-induced current response b...More data for this Ligand-Target Pair