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Found 17 Enz. Inhib. hit(s) with all data for entry = 50045073
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50044262(CHEMBL3314084)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human recombinant COX-2 assessed as decrease in prostaglandin production using arachidonic acid as substrate incubated with enzyme for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50044262(CHEMBL3314084)
Affinity DataIC50:  4.70nMAssay Description:Inhibition of ovine COX-1 assessed as decrease in prostaglandin production using arachidonic acid as substrate incubated with enzyme for 10 mins prio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50044264(CHEMBL3314086)
Affinity DataIC50:  5.80nMAssay Description:Inhibition of human recombinant COX-2 assessed as decrease in prostaglandin production using arachidonic acid as substrate incubated with enzyme for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50044266(CHEMBL3314088)
Affinity DataIC50:  20nMAssay Description:Inhibition of human recombinant COX-2 assessed as decrease in prostaglandin production using arachidonic acid as substrate incubated with enzyme for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50044265(CHEMBL3314087)
Affinity DataIC50:  29nMAssay Description:Inhibition of human recombinant COX-2 assessed as decrease in prostaglandin production using arachidonic acid as substrate incubated with enzyme for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  40nMAssay Description:Inhibition of human recombinant COX-2 assessed as decrease in prostaglandin production using arachidonic acid as substrate incubated with enzyme for ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  80nMAssay Description:Inhibition of ovine COX-1 assessed as decrease in prostaglandin production using arachidonic acid as substrate incubated with enzyme for 10 mins prio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50044263(CHEMBL3314085)
Affinity DataIC50:  630nMAssay Description:Inhibition of ovine COX-1 assessed as decrease in prostaglandin production using arachidonic acid as substrate incubated with enzyme for 10 mins prio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50044264(CHEMBL3314086)
Affinity DataIC50:  650nMAssay Description:Inhibition of ovine COX-1 assessed as decrease in prostaglandin production using arachidonic acid as substrate incubated with enzyme for 10 mins prio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM17638(2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl...)
Affinity DataIC50:  960nMAssay Description:Inhibition of human recombinant COX-2 assessed as decrease in prostaglandin production using arachidonic acid as substrate incubated with enzyme for ...More data for this Ligand-Target Pair
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50044265(CHEMBL3314087)
Affinity DataIC50:  1.35E+3nMAssay Description:Inhibition of ovine COX-1 assessed as decrease in prostaglandin production using arachidonic acid as substrate incubated with enzyme for 10 mins prio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50044266(CHEMBL3314088)
Affinity DataIC50:  6.75E+3nMAssay Description:Inhibition of ovine COX-1 assessed as decrease in prostaglandin production using arachidonic acid as substrate incubated with enzyme for 10 mins prio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50044263(CHEMBL3314085)
Affinity DataIC50:  7.60E+3nMAssay Description:Inhibition of human recombinant COX-2 assessed as decrease in prostaglandin production using arachidonic acid as substrate incubated with enzyme for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50044267(CHEMBL3314089)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human recombinant COX-2 assessed as decrease in prostaglandin production using arachidonic acid as substrate incubated with enzyme for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50044267(CHEMBL3314089)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of ovine COX-1 assessed as decrease in prostaglandin production using arachidonic acid as substrate incubated with enzyme for 10 mins prio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM11639(4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyraz...)
Affinity DataIC50:  1.50E+4nMAssay Description:Inhibition of ovine COX-1 assessed as decrease in prostaglandin production using arachidonic acid as substrate incubated with enzyme for 10 mins prio...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Homo sapiens (Human))
Guru Nanak Dev University

Curated by ChEMBL
LigandPNGBDBM50140257(5,7-Dihydroxy-8-methoxy-2-phenyl-chromen-4-one | 5...)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of human recombinant COX-2 assessed as decrease in prostaglandin production using arachidonic acid as substrate incubated with enzyme for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed