Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 6128
TargetTyrosine-protein kinase CSK(Human)
University of Delhi

LigandPNGBDBM50142887(1-tert-Butyl-3-(4-chloro-phenyl)-1H-pyrazolo[3,4-d...)
Affinity DataIC50: 500nMpH: 7.5 T: 2°CAssay Description:The kinase reaction was initiated with the incubation of the 2.5 µL of the reaction cocktail (0.7 nM of His6-Src kinase domain in kinase buffer)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
University of Delhi

LigandPNGBDBM2579(CHEMBL388978 | Staurosporine, 8 | Staurosporin, 4 ...)
Affinity DataIC50: 600nMpH: 7.5 T: 2°CAssay Description:The kinase reaction was initiated with the incubation of the 2.5 µL of the reaction cocktail (0.7 nM of His6-Src kinase domain in kinase buffer)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
University of Delhi

LigandPNGBDBM110206(1-[2-(Dimethylamino)ethyl]-5-(2-hydroxy-4-methoxyb...)
Affinity DataIC50: 1.25E+4nMpH: 7.5 T: 2°CAssay Description:The kinase reaction was initiated with the incubation of the 2.5 µL of the reaction cocktail (0.7 nM of His6-Src kinase domain in kinase buffer)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
University of Delhi

LigandPNGBDBM110208(5-(2-Hydroxy-4-methoxybenzoyl)-1-(2-hydroxyethyl)p...)
Affinity DataIC50: 1.99E+4nMpH: 7.5 T: 2°CAssay Description:The kinase reaction was initiated with the incubation of the 2.5 µL of the reaction cocktail (0.7 nM of His6-Src kinase domain in kinase buffer)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
University of Delhi

LigandPNGBDBM110215((E)-1-Cyclohexyl-5-[(cyclohexylimino)(2-hydroxyphe...)
Affinity DataIC50: 2.01E+4nMpH: 7.5 T: 2°CAssay Description:The kinase reaction was initiated with the incubation of the 2.5 µL of the reaction cocktail (0.7 nM of His6-Src kinase domain in kinase buffer)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
University of Delhi

LigandPNGBDBM110199(5-(2-Hydroxybenzoyl)-1-isopropylpyridin-2(1H)-one ...)
Affinity DataIC50: 2.18E+4nMpH: 7.5 T: 2°CAssay Description:The kinase reaction was initiated with the incubation of the 2.5 µL of the reaction cocktail (0.7 nM of His6-Src kinase domain in kinase buffer)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
University of Delhi

LigandPNGBDBM110213(t-Butyl [2-{5-(2-hydroxy-5-methoxybenzoyl)-2-oxopy...)
Affinity DataIC50: 2.19E+4nMpH: 7.5 T: 2°CAssay Description:The kinase reaction was initiated with the incubation of the 2.5 µL of the reaction cocktail (0.7 nM of His6-Src kinase domain in kinase buffer)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
University of Delhi

LigandPNGBDBM110209(5-(2,5-Dihydroxybenzoyl)-1-hexylpyridin-2(1H)-one ...)
Affinity DataIC50: 2.21E+4nMpH: 7.5 T: 2°CAssay Description:The kinase reaction was initiated with the incubation of the 2.5 µL of the reaction cocktail (0.7 nM of His6-Src kinase domain in kinase buffer)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
University of Delhi

LigandPNGBDBM110211(1-Hexyl-5-(2-hydroxy-5-methoxybenzoyl)pyridin-2(1H...)
Affinity DataIC50: 2.35E+4nMpH: 7.5 T: 2°CAssay Description:The kinase reaction was initiated with the incubation of the 2.5 µL of the reaction cocktail (0.7 nM of His6-Src kinase domain in kinase buffer)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
University of Delhi

LigandPNGBDBM110212(1-Cyclohexyl-5-(2-hydroxy-5-methoxybenzoyl)pyridin...)
Affinity DataIC50: 2.48E+4nMpH: 7.5 T: 2°CAssay Description:The kinase reaction was initiated with the incubation of the 2.5 µL of the reaction cocktail (0.7 nM of His6-Src kinase domain in kinase buffer)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
University of Delhi

LigandPNGBDBM110200(1-Cyclohexyl-5-(2-hydroxybenzoyl)pyridin-2(1H)-one...)
Affinity DataIC50: 2.54E+4nMpH: 7.5 T: 2°CAssay Description:The kinase reaction was initiated with the incubation of the 2.5 µL of the reaction cocktail (0.7 nM of His6-Src kinase domain in kinase buffer)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
University of Delhi

LigandPNGBDBM110210(5-(2,5-Dihydroxybenzoyl)-1-isopropylpyridin-2(1H)-...)
Affinity DataIC50: 2.61E+4nMpH: 7.5 T: 2°CAssay Description:The kinase reaction was initiated with the incubation of the 2.5 µL of the reaction cocktail (0.7 nM of His6-Src kinase domain in kinase buffer)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
University of Delhi

LigandPNGBDBM110207(t-Butyl [2-{5-(2-hydroxy-4-methoxybenzoyl)-2-oxopy...)
Affinity DataIC50: 2.76E+4nMpH: 7.5 T: 2°CAssay Description:The kinase reaction was initiated with the incubation of the 2.5 µL of the reaction cocktail (0.7 nM of His6-Src kinase domain in kinase buffer)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
University of Delhi

LigandPNGBDBM110202(5-(2,4-Dihydroxybenzoyl)-1-hexylpyridin-2(1H)-one ...)
Affinity DataIC50: 2.77E+4nMpH: 7.5 T: 2°CAssay Description:The kinase reaction was initiated with the incubation of the 2.5 µL of the reaction cocktail (0.7 nM of His6-Src kinase domain in kinase buffer)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
University of Delhi

LigandPNGBDBM110198(1-Hexyl-5-(2-hydroxybenzoyl)pyridin-2(1H)-one (28))
Affinity DataIC50: 2.81E+4nMpH: 7.5 T: 2°CAssay Description:The kinase reaction was initiated with the incubation of the 2.5 µL of the reaction cocktail (0.7 nM of His6-Src kinase domain in kinase buffer)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
University of Delhi

LigandPNGBDBM110201(1-[2-(Dimethylamino)ethyl]-5-(2-hydroxybenzoyl)pyr...)
Affinity DataIC50: 2.82E+4nMpH: 7.5 T: 2°CAssay Description:The kinase reaction was initiated with the incubation of the 2.5 µL of the reaction cocktail (0.7 nM of His6-Src kinase domain in kinase buffer)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
University of Delhi

LigandPNGBDBM110204(1-Hexyl-5-(2-hydroxy-4-methoxybenzoyl)pyridin-2(1H...)
Affinity DataIC50: 3.41E+4nMpH: 7.5 T: 2°CAssay Description:The kinase reaction was initiated with the incubation of the 2.5 µL of the reaction cocktail (0.7 nM of His6-Src kinase domain in kinase buffer)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
University of Delhi

LigandPNGBDBM110214((E)-5-[(2-Hydroxyphenyl)(isopropylimino)methyl]-1-...)
Affinity DataIC50: 3.79E+4nMpH: 7.5 T: 2°CAssay Description:The kinase reaction was initiated with the incubation of the 2.5 µL of the reaction cocktail (0.7 nM of His6-Src kinase domain in kinase buffer)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
University of Delhi

LigandPNGBDBM110205(5-(2-Hydroxy-4-methoxybenzoyl)-1-isopropylpyridin-...)
Affinity DataIC50: 4.70E+4nMpH: 7.5 T: 2°CAssay Description:The kinase reaction was initiated with the incubation of the 2.5 µL of the reaction cocktail (0.7 nM of His6-Src kinase domain in kinase buffer)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase CSK(Human)
University of Delhi

LigandPNGBDBM110203(t-Butyl [2-{5-(2,4-dihydroxybenzoyl)-2-oxopyridin-...)
Affinity DataIC50: 5.78E+4nMpH: 7.5 T: 2°CAssay Description:The kinase reaction was initiated with the incubation of the 2.5 µL of the reaction cocktail (0.7 nM of His6-Src kinase domain in kinase buffer)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetEpidermal growth factor receptor [1-973](Human)
University of Delhi

LigandPNGBDBM110206(1-[2-(Dimethylamino)ethyl]-5-(2-hydroxy-4-methoxyb...)
Affinity DataIC50: 3.00E+5nMpH: 7.0Assay Description:EGFR was incubated with 8 mM MOPS (pH 7.0), 0.2 mM EDTA, 10 mM MnCl2, 0.1 mg/mL poly(Glu, Tyr) 4:1. MAPK1 was incubated with 25 mM Tris (pH 7.5), 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
Target3-phosphoinositide-dependent protein kinase 1(Human)
University of Delhi

LigandPNGBDBM110206(1-[2-(Dimethylamino)ethyl]-5-(2-hydroxy-4-methoxyb...)
Affinity DataIC50: 3.00E+5nMpH: 7.0Assay Description:EGFR was incubated with 8 mM MOPS (pH 7.0), 0.2 mM EDTA, 10 mM MnCl2, 0.1 mg/mL poly(Glu, Tyr) 4:1. MAPK1 was incubated with 25 mM Tris (pH 7.5), 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 1(Human)
University of Delhi

LigandPNGBDBM110206(1-[2-(Dimethylamino)ethyl]-5-(2-hydroxy-4-methoxyb...)
Affinity DataIC50: 3.00E+5nMpH: 7.0Assay Description:EGFR was incubated with 8 mM MOPS (pH 7.0), 0.2 mM EDTA, 10 mM MnCl2, 0.1 mg/mL poly(Glu, Tyr) 4:1. MAPK1 was incubated with 25 mM Tris (pH 7.5), 0.0...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2014
Entry Details Article
PubMed