Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50044127
TargetRho-associated protein kinase 2(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004422(CHEMBL3238167)
Affinity DataIC50: 24nMAssay Description:Inhibition of truncated ROCK-2 (unknown origin) after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004423(CHEMBL3238168)
Affinity DataIC50: 36nMAssay Description:Inhibition of truncated ROCK-2 (unknown origin) after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50309126(2-(4-(6-(pyridin-4-yl)-3-(pyrrolidin-1-yl)pyrazin-...)
Affinity DataIC50: 39nMAssay Description:Inhibition of truncated ROCK-2 (unknown origin) after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50319005((R)-4-(1-aminoethyl)-N-(1H-pyrrolo[2,3-b]pyridin-4...)
Affinity DataIC50: 58nMAssay Description:Inhibition of truncated ROCK-2 (unknown origin) after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004421(CHEMBL3238166)
Affinity DataIC50: 65nMAssay Description:Inhibition of truncated ROCK-2 (unknown origin) after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004419(CHEMBL3238164)
Affinity DataIC50: 68nMAssay Description:Inhibition of truncated ROCK-2 (unknown origin) after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004420(CHEMBL3238165)
Affinity DataIC50: 75nMAssay Description:Inhibition of truncated ROCK-2 (unknown origin) after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004418(CHEMBL3238163)
Affinity DataIC50: 76nMAssay Description:Inhibition of truncated ROCK-2 (unknown origin) after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004422(CHEMBL3238167)
Affinity DataIC50: 105nMAssay Description:Inhibition of truncated ROCK-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50319005((R)-4-(1-aminoethyl)-N-(1H-pyrrolo[2,3-b]pyridin-4...)
Affinity DataIC50: 120nMAssay Description:Inhibition of truncated ROCK-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004423(CHEMBL3238168)
Affinity DataIC50: 140nMAssay Description:Inhibition of truncated ROCK-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50319005((R)-4-(1-aminoethyl)-N-(1H-pyrrolo[2,3-b]pyridin-4...)
Affinity DataEC50:  150nMAssay Description:Inhibition of ROCK-2 in human GTM3 cells measured up to 2 days by cell impedance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004421(CHEMBL3238166)
Affinity DataIC50: 203nMAssay Description:Inhibition of truncated ROCK-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004422(CHEMBL3238167)
Affinity DataEC50:  260nMAssay Description:Inhibition of ROCK-2 in human GTM3 cells measured up to 2 days by cell impedance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004418(CHEMBL3238163)
Affinity DataIC50: 288nMAssay Description:Inhibition of truncated ROCK-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004420(CHEMBL3238165)
Affinity DataIC50: 346nMAssay Description:Inhibition of truncated ROCK-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004419(CHEMBL3238164)
Affinity DataIC50: 350nMAssay Description:Inhibition of truncated ROCK-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004423(CHEMBL3238168)
Affinity DataEC50:  380nMAssay Description:Inhibition of ROCK-2 in human GTM3 cells measured up to 2 days by cell impedance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004421(CHEMBL3238166)
Affinity DataEC50:  416nMAssay Description:Inhibition of ROCK-2 in human GTM3 cells measured up to 2 days by cell impedance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetRho-associated protein kinase 1(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50309126(2-(4-(6-(pyridin-4-yl)-3-(pyrrolidin-1-yl)pyrazin-...)
Affinity DataIC50: 570nMAssay Description:Inhibition of truncated ROCK-1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50309126(2-(4-(6-(pyridin-4-yl)-3-(pyrrolidin-1-yl)pyrazin-...)
Affinity DataEC50:  680nMAssay Description:Inhibition of ROCK-2 in human GTM3 cells measured up to 2 days by cell impedance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004420(CHEMBL3238165)
Affinity DataEC50:  760nMAssay Description:Inhibition of ROCK-2 in human GTM3 cells measured up to 2 days by cell impedance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004418(CHEMBL3238163)
Affinity DataEC50:  1.50E+3nMAssay Description:Inhibition of ROCK-2 in human GTM3 cells measured up to 2 days by cell impedance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Alcon Laboratories

Curated by ChEMBL
LigandPNGBDBM50004419(CHEMBL3238164)
Affinity DataEC50:  1.70E+3nMAssay Description:Inhibition of ROCK-2 in human GTM3 cells measured up to 2 days by cell impedance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2015
Entry Details Article
PubMed