Compile Data Set for Download or QSAR
Report error Found 74 Enz. Inhib. hit(s) with all data for entry = 50049260
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50022815BDBM50022815((3S,6S,9S,12R,15S,18S,21S,24S,30S,33S)-30-ethyl-33...)
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell membrane vesicles assessed as reduction in ATP or AMP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50103521BDBM50103521(CHEBI:8228 | Actos | Duetact | Pioglitazone | US20...)
Affinity DataIC50: 400nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50012957BDBM50012957(1-((p-(2-(5-chloro-o-anisamido)ethyl)phenyl)sulfon...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell membrane vesicles assessed as reduction in ATP or AMP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50088504BDBM50088504(CHEBI:45409 | A-84538 | ABBOTT-84538 | Norvir | Ri...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50213021BDBM50213021(CHEBI:63621 | Fortovase | Invirase | Ro-31-8959 | ...)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell membrane vesicles assessed as reduction in ATP or AMP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 151585BDBM151585(US8987315, Ketoconazole | US9180183, Ketoconazole ...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50030474BDBM50030474(US9562012, rosiglitazone | CHEBI:50122 | Avandamet...)
Affinity DataIC50: 3.75E+3nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50085045BDBM50085045(5-((4-((6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-...)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5445BDBM5445(N-{3-chloro-4-[(3-fluorophenyl)methoxy]phenyl}-6-(...)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50069447BDBM50069447(2-{3-[4-(3-chlorophenyl)piperazin-1-yl]propyl}-5-e...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell membrane vesicles assessed as reduction in ATP or AMP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50042235BDBM50042235(2-butyl-3-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4...)
Affinity DataIC50: 7.31E+3nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101815BDBM50101815(CHEBI:7550 | Nicardipine)
Affinity DataIC50: 7.90E+3nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 16673BDBM16673(BAY439006 | CHEMBL1336 | BAY 43-9006 | 4-[4-({[4-c...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 39347BDBM39347(MLS000028708 | cid_32798 | SMR000058745 | CLOBETAS...)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf21 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 82258BDBM82258(NSC_3961 | CAS_114798-26-4 | Losartan)
Affinity DataIC50: 8.53E+3nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 22041BDBM22041(2-[6-chloro-2-(4-chlorophenyl)imidazo[1,2-a]pyridi...)
Affinity DataIC50: 9.20E+3nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf21 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50237628BDBM50237628(CHEBI:6970 | Mometasone)
Affinity DataIC50: 9.30E+3nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell membrane vesicles assessed as reduction in ATP or AMP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50391000BDBM50391000(CB-01-11 | RIFAMYCIN)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell membrane vesicles assessed as reduction in ATP or AMP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 79181BDBM79181(cid_2913535 | TRIFLUOPERAZINE | SMR000059133 | MLS...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf21 cell membrane vesicles assessed as reduction in ATP-dependent [3H]-tauroc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31774BDBM31774(cid_2812 | CHEMBL104 | Canesten | Mycelex | Lotrim...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf21 cell membrane vesicles assessed as reduction in ATP-dependent [3H]-tauroc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 8903BDBM8903(CHEMBL103 | (1S,2R,10S,11S,14S,15S)-14-acetyl-2,15...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf21 cell membrane vesicles assessed as reduction in ATP-dependent [3H]-tauroc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101971BDBM50101971(CHEBI:7575 | BAY-E-9736 | Nimodipine | Nimotop)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell membrane vesicles assessed as reduction in ATP or AMP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 53488BDBM53488(MLS000028668 | BECLOMETHASONE | (8S,9R,10S,11S,13S...)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell membrane vesicles assessed as reduction in ATP or AMP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 21674BDBM21674(Chenodeoxycholic Acid | CDCA | (4R)-4-[(1S,2S,5R,7...)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell membrane vesicles assessed as reduction in ATP or AMP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5447BDBM5447(ZD1839 | N-(3-chloro-4-fluorophenyl)-7-methoxy-6-[...)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50237626BDBM50237626(CHEBI:9342 | Anturan | Anturane | Sulfinpyrazone |...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell membrane vesicles assessed as reduction in ATP or AMP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50009073BDBM50009073(cyclopentyl 3-(2-methoxy-4-((o-tolylsulfonyl)carba...)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18860BDBM18860(triothyrone | (2S)-2-amino-3-[4-(4-hydroxy-3-iodop...)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf21 cell membrane vesicles assessed as reduction in ATP-dependent [3H]-tauroc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50237625BDBM50237625(Etomoxir)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of BSEP (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50061306BDBM50061306(CHEMBL1205 | Viracept | (3S,4aS,8aS)-2-[(2R,3R)-2-...)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378783BDBM50378783(CLOFAZIMINE)
Affinity DataIC50: 1.29E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31688BDBM31688(Erythromycin Estolate)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31773BDBM31773(ECONAZOLE | cid_68589 | Pevaryl | Gyno-pevaryl | E...)
Affinity DataIC50: 1.34E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell membrane vesicles assessed as reduction in ATP or AMP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001839BDBM50001839(CHEMBL428647 | taxol | PACLITAXEL)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50158460BDBM50158460(cid_2333 | Benzbromarone | 3,5-dibromo-4-hydroxyph...)
Affinity DataIC50: 1.59E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell membrane vesicles assessed as reduction in ATP or AMP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50043280BDBM50043280(4'-[(1,7'-dimethyl-2'-propyl-1H,3'H-2,5'-bibenzimi...)
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50370232BDBM50370232(BA-41166E | L-5103 | Rifadin | Rifampicin | RIFAMP...)
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell membrane vesicles assessed as reduction in ATP or AMP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50237624BDBM50237624(CHEMBL4066812)
Affinity DataIC50: 1.87E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 34168BDBM34168(cid_53232 | SMR000058779 | MLS000069585 | LOVASTAT...)
Affinity DataIC50: 1.93E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50067593BDBM50067593(CHEBI:44032 | Crixivan | Indinavir | L-735524 | MK...)
Affinity DataIC50: 2.12E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50139181BDBM50139181(2,2-dimethylbutyric acid, 8-ester with (4R,6R)-6-(...)
Affinity DataIC50: 2.47E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 13530BDBM13530(cid_5291 | STI571 | N-(4-methyl-3-{[4-(pyridin-3-y...)
Affinity DataIC50: 2.51E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50237607BDBM50237607(CHEBI:45367 | Ansamycin | LM-427 | Mycobutin | Rif...)
Affinity DataIC50: 2.67E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50165019BDBM50165019(4-(diethylamino)but-2-yn-1-yl cyclohexyl(hydroxy)p...)
Affinity DataIC50: 2.74E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50334788BDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50: 2.82E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50061101BDBM50061101(4-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(2-methoxyph...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell membrane vesicles assessed as reduction in ATP or AMP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 18525BDBM18525(N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...)
Affinity DataIC50: 2.93E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell membrane vesicles assessed as reduction in ATP or AMP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50378137BDBM50378137(Ketek | TELITHROMYCIN)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell membrane vesicles assessed as reduction in ATP or AMP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50101963BDBM50101963(CHEBI:76917 | BAY-K-5552 | Nisoldipine | Sular)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell plasma membrane vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
TargetBile salt export pump(Human)
Pfizer

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50237590BDBM50237590(CHEBI:5383 | Amaryl | Glimepiride | HOE-490 | Nidd...)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of recombinant human BSEP expressed in baculovirus infected sf9 cell membrane vesicles assessed as reduction in ATP or AMP-dependent [3H]-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2019
Entry Details Article
PubMed
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