Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50045097
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50153713(3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID | [3...)
Affinity DataIC50: 32nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMalate dehydrogenase(Thermus thermophilus)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM59100(Bi-ligand, 3)
Affinity DataIC50: 400nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetMalate dehydrogenase(Thermus thermophilus)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044967(CHEMBL3309759)
Affinity DataIC50: 500nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetMalate dehydrogenase(Thermus thermophilus)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044973(CHEMBL3309761)
Affinity DataIC50: 700nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetMalate dehydrogenase(Thermus thermophilus)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044971(CHEMBL3309760)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetMalate dehydrogenase(Thermus thermophilus)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044974(CHEMBL3309762)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044976(CHEMBL2316879)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044967(CHEMBL3309759)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044973(CHEMBL3309761)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetMalate dehydrogenase(Thermus thermophilus)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044975(CHEMBL3309763)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044971(CHEMBL3309760)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044975(CHEMBL3309763)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM59100(Bi-ligand, 3)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044976(CHEMBL2316879)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in presence of 0.01% Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetMalate dehydrogenase(Thermus thermophilus)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044976(CHEMBL2316879)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in absence of 0.01% Triton X100 by U...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044975(CHEMBL3309763)
Affinity DataIC50: 6.10E+3nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in presence of 0.01% Tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044976(CHEMBL2316879)
Affinity DataKi:  7.70E+3nMAssay Description:Uncompetitive inhibition of His-tagged Escherichia coli DXR at 1 to 8 uM pre-incubated for 2 mins before reaction initiation in presence of 160 uM NA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
TargetMalate dehydrogenase(Thermus thermophilus)
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044976(CHEMBL2316879)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of Thermus flavus MDH pre-incubated for 4 mins before reaction initiation in presence of OAA and NAPH in presence of 0.01% Triton X100 by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
University of Strasburg

Curated by ChEMBL
LigandPNGBDBM50044974(CHEMBL3309762)
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of His-tagged Escherichia coli DXR pre-incubated for 2 mins before reaction initiation in presence of 160 uM NADPH in absence of 0.01% Tri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/22/2016
Entry Details Article
PubMed