Compile Data Set for Download or QSAR
Report error Found 58 Enz. Inhib. hit(s) with all data for entry = 50045187
LigandChemical structure of BindingDB Monomer ID 50048722BDBM50048722(CHEMBL3319646)
Affinity DataIC50: 2nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048713BDBM50048713(CHEMBL3319490)
Affinity DataIC50: 3nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048710BDBM50048710(CHEMBL3319485)
Affinity DataIC50: 4nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048713BDBM50048713(CHEMBL3319490)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant PI3Kbeta assessed as depletion of ATP substrate by Ultra Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048720BDBM50048720(CHEMBL3319644)
Affinity DataIC50: 7nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048712BDBM50048712(CHEMBL3319489)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant PI3Kbeta assessed as depletion of ATP substrate by Ultra Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048710BDBM50048710(CHEMBL3319485)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant PI3Kbeta assessed as depletion of ATP substrate by Ultra Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048838BDBM50048838(CHEMBL3319494)
Affinity DataIC50: 8nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048709BDBM50048709(CHEMBL3318715)
Affinity DataIC50: 8nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048709BDBM50048709(CHEMBL3318715)
Affinity DataIC50: 8nMAssay Description:Inhibition of human recombinant PI3Kbeta assessed as depletion of ATP substrate by Ultra Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048717BDBM50048717(CHEMBL3319642)
Affinity DataIC50: 9nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048719BDBM50048719(CHEMBL3319643)
Affinity DataIC50: 10nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048708BDBM50048708(CHEMBL3318711)
Affinity DataIC50: 11nMAssay Description:Inhibition of human recombinant PI3Kbeta assessed as depletion of ATP substrate by Ultra Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048835BDBM50048835(CHEMBL3319492)
Affinity DataIC50: 11nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048834BDBM50048834(CHEMBL3319491)
Affinity DataIC50: 11nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048721BDBM50048721(CHEMBL3319645)
Affinity DataIC50: 12nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048716BDBM50048716(CHEMBL3319641)
Affinity DataIC50: 17nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50447094BDBM50447094(CHEMBL1972466)
Affinity DataIC50: 22nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048723BDBM50048723(CHEMBL3319647)
Affinity DataIC50: 23nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048839BDBM50048839(CHEMBL3319495)
Affinity DataIC50: 25nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048836BDBM50048836(CHEMBL3319493)
Affinity DataIC50: 25nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048840BDBM50048840(CHEMBL3319496)
Affinity DataIC50: 29nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048713BDBM50048713(CHEMBL3319490)
Affinity DataIC50: 32nMAssay Description:Inhibition of human recombinant PI3Kdelta assessed as depletion of ATP substrate by Ultra Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048712BDBM50048712(CHEMBL3319489)
Affinity DataIC50: 34nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048711BDBM50048711(CHEMBL3319486)
Affinity DataIC50: 37nMAssay Description:Inhibition of human recombinant PI3Kbeta assessed as depletion of ATP substrate by Ultra Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048830BDBM50048830(CHEMBL3319487)
Affinity DataIC50: 39nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50395821BDBM50395821(CHEMBL2165191)
Affinity DataIC50: 40nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048712BDBM50048712(CHEMBL3319489)
Affinity DataIC50: 45nMAssay Description:Inhibition of human recombinant PI3Kdelta assessed as depletion of ATP substrate by Ultra Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048710BDBM50048710(CHEMBL3319485)
Affinity DataIC50: 51nMAssay Description:Inhibition of human recombinant PI3Kdelta assessed as depletion of ATP substrate by Ultra Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048711BDBM50048711(CHEMBL3319486)
Affinity DataIC50: 62nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048832BDBM50048832(CHEMBL3319488)
Affinity DataIC50: 73nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048826BDBM50048826(CHEMBL3319648)
Affinity DataIC50: 74nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048713BDBM50048713(CHEMBL3319490)
Affinity DataIC50: 75nMAssay Description:Inhibition of human recombinant PI3Kalpha assessed as depletion of ATP substrate by Ultra Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048718BDBM50048718(CHEMBL3317473)
Affinity DataIC50: 75nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048714BDBM50048714(CHEMBL3319639)
Affinity DataIC50: 81nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048709BDBM50048709(CHEMBL3318715)
Affinity DataIC50: 85nMAssay Description:Inhibition of human recombinant PI3Kdelta assessed as depletion of ATP substrate by Ultra Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048710BDBM50048710(CHEMBL3319485)
Affinity DataIC50: 92nMAssay Description:Inhibition of human recombinant PI3Kalpha assessed as depletion of ATP substrate by Ultra Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048708BDBM50048708(CHEMBL3318711)
Affinity DataIC50: 110nMAssay Description:Inhibition of human recombinant PI3Kdelta assessed as depletion of ATP substrate by Ultra Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048708BDBM50048708(CHEMBL3318711)
Affinity DataIC50: 156nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048715BDBM50048715(CHEMBL3319640)
Affinity DataIC50: 190nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048711BDBM50048711(CHEMBL3319486)
Affinity DataIC50: 230nMAssay Description:Inhibition of human recombinant PI3Kdelta assessed as depletion of ATP substrate by Ultra Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048712BDBM50048712(CHEMBL3319489)
Affinity DataIC50: 340nMAssay Description:Inhibition of human recombinant PI3Kalpha assessed as depletion of ATP substrate by Ultra Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048709BDBM50048709(CHEMBL3318715)
Affinity DataIC50: 370nMAssay Description:Inhibition of human recombinant PI3Kalpha assessed as depletion of ATP substrate by Ultra Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048713BDBM50048713(CHEMBL3319490)
Affinity DataIC50: 510nMAssay Description:Inhibition of human recombinant PI3Kgamma assessed as depletion of ATP substrate by Ultra Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048829BDBM50048829(CHEMBL3319649)
Affinity DataIC50: 530nMAssay Description:Inhibition of PI3Kbeta in human MAD-MB-468 cells assessed as inhibition of Ser473 Akt phosphorylation by cellular potency assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048708BDBM50048708(CHEMBL3318711)
Affinity DataIC50: 560nMAssay Description:Inhibition of human recombinant PI3Kalpha assessed as depletion of ATP substrate by Ultra Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048710BDBM50048710(CHEMBL3319485)
Affinity DataIC50: 670nMAssay Description:Inhibition of human recombinant PI3Kgamma assessed as depletion of ATP substrate by Ultra Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048710BDBM50048710(CHEMBL3319485)
Affinity DataIC50: 970nMAssay Description:Inhibition of PI3Kalpha in human BT474 cells assessed as inhibition of Tyr308 Akt phosphorylation after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048713BDBM50048713(CHEMBL3319490)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of PI3Kalpha in human BT474 cells assessed as inhibition of Tyr308 Akt phosphorylation after 2 hrs by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50048711BDBM50048711(CHEMBL3319486)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant PI3Kalpha assessed as depletion of ATP substrate by Ultra Glo luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/25/2016
Entry Details Article
PubMed
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