Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50045296
Target5-hydroxytryptamine receptor 7(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055575(CHEMBL3321794)
Affinity DataKi:  0.700nMAssay Description:Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055574(CHEMBL3321798)
Affinity DataKi:  2.70nMAssay Description:Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267832(1-[4-(3,4-Dihydroisoquinolin-2(1H)-yl)butyl]-1,3-d...)
Affinity DataKi:  7nMAssay Description:Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM10755([3H]-5-HT | 5-Hydroxy Tryptamine | 2-imino-1-methy...)
Affinity DataEC50:  17nMAssay Description:Agonist activity at human 5-HT7 expressed in HEK-293 cells assessed as increase in cAMP level after 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055580(CHEMBL3321778)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055581(CHEMBL3321777)
Affinity DataKi:  28nMAssay Description:Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055578(CHEMBL3321795)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055579(CHEMBL3321793)
Affinity DataKi:  36nMAssay Description:Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055577(CHEMBL3321796)
Affinity DataKi:  41nMAssay Description:Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055574(CHEMBL3321798)
Affinity DataEC50:  60nMAssay Description:Agonist activity at human 5-HT7 expressed in HEK-293 cells assessed as increase in cAMP level after 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055576(CHEMBL3321797)
Affinity DataKi:  62nMAssay Description:Displacement of [3H]LSD from human 5-HT7 expressed in HEK-293 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50267832(1-[4-(3,4-Dihydroisoquinolin-2(1H)-yl)butyl]-1,3-d...)
Affinity DataKi:  219nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A expressed in CHO-K1 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055575(CHEMBL3321794)
Affinity DataEC50:  230nMAssay Description:Agonist activity at human 5-HT7 expressed in HEK-293 cells assessed as increase in cAMP level after 45 mins by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50024204(MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...)
Affinity DataIC50: 290nMAssay Description:Antagonist activity at human 5-HT7 expressed in HEK-293 cells assessed as inhibition in serotonin-induced increase in cAMP level after 45 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055578(CHEMBL3321795)
Affinity DataKi:  470nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A expressed in CHO-K1 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055577(CHEMBL3321796)
Affinity DataKi:  491nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A expressed in CHO-K1 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055581(CHEMBL3321777)
Affinity DataKi:  523nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A expressed in CHO-K1 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055580(CHEMBL3321778)
Affinity DataKi:  576nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A expressed in CHO-K1 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055576(CHEMBL3321797)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A expressed in CHO-K1 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055574(CHEMBL3321798)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A expressed in CHO-K1 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055579(CHEMBL3321793)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A expressed in CHO-K1 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055575(CHEMBL3321794)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]-8-OH-DPAT from human 5-HT1A expressed in CHO-K1 cells after 120 mins by scintillation spectrometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055575(CHEMBL3321794)
Affinity DataIC50: 2.20E+3nMAssay Description:Antagonist activity at human 5-HT7 expressed in HEK-293 cells assessed as inhibition in serotonin-induced increase in cAMP level after 45 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Human)
Universidad Complutense De Madrid

Curated by ChEMBL
LigandPNGBDBM50055574(CHEMBL3321798)
Affinity DataIC50: 2.30E+3nMAssay Description:Antagonist activity at human 5-HT7 expressed in HEK-293 cells assessed as inhibition in serotonin-induced increase in cAMP level after 45 mins by HTR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2016
Entry Details Article
PubMed