Compile Data Set for Download or QSAR
Report error Found 56 Enz. Inhib. hit(s) with all data for entry = 50045304
TargetKappa-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataIC50: 0.300nMAssay Description:Agonist activity at human kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50001683(CHEMBL294616 | 13-[2-Amino-3-(4-hydroxy-phenyl)-pr...)
Affinity DataIC50: 0.900nMAssay Description:Agonist activity at human delta opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50000788([17-(2,3-3H-2-propenyl)]-4, 5a -epoxy-3,14-dihydro...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]-naloxone from rat mu opioid receptor expressed in HEK cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataIC50: 5nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production after 30 mins by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50000092(Analog of 14-(Arylhydroxyamino)codeinone | 4-methy...)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055967(CHEMBL3325714)
Affinity DataEC50:  41nMAssay Description:Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055966(CHEMBL3325715)
Affinity DataEC50:  41nMAssay Description:Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055965(CHEMBL3325716)
Affinity DataEC50:  41nMAssay Description:Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055966(CHEMBL3325715)
Affinity DataEC50:  100nMAssay Description:Agonist activity at myc-tagged mu opioid receptor (unknown origin) expressed in AtT-20 cells assessed as induction of membrane potential hyperpolariz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055964(CHEMBL3325841)
Affinity DataEC50:  100nMAssay Description:Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055968(CHEMBL3325713)
Affinity DataEC50:  150nMAssay Description:Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055965(CHEMBL3325716)
Affinity DataEC50:  200nMAssay Description:Agonist activity at myc-tagged mu opioid receptor (unknown origin) expressed in AtT-20 cells assessed as induction of membrane potential hyperpolariz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055972(CHEMBL3325710)
Affinity DataEC50:  370nMAssay Description:Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055965(CHEMBL3325716)
Affinity DataIC50: 370nMAssay Description:Agonist activity at human kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055969(CHEMBL3325719)
Affinity DataEC50:  370nMAssay Description:Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055973(CHEMBL3325707)
Affinity DataEC50:  370nMAssay Description:Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055967(CHEMBL3325714)
Affinity DataIC50: 410nMAssay Description:Agonist activity at human kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055967(CHEMBL3325714)
Affinity DataKi:  470nMAssay Description:Displacement of [3H]-naloxone from rat mu opioid receptor expressed in HEK cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055966(CHEMBL3325715)
Affinity DataIC50: 570nMAssay Description:Agonist activity at human kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055966(CHEMBL3325715)
Affinity DataKi:  610nMAssay Description:Displacement of [3H]-naloxone from rat mu opioid receptor expressed in HEK cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055967(CHEMBL3325714)
Affinity DataIC50: 730nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production after 30 mins by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055965(CHEMBL3325716)
Affinity DataKi:  740nMAssay Description:Displacement of [3H]-naloxone from rat mu opioid receptor expressed in HEK cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055964(CHEMBL3325841)
Affinity DataIC50: 1.10E+3nMAssay Description:Agonist activity at human kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055989(CHEMBL3325700)
Affinity DataEC50:  1.12E+3nMAssay Description:Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055969(CHEMBL3325719)
Affinity DataKi:  1.30E+3nMAssay Description:Displacement of [3H]-naloxone from rat mu opioid receptor expressed in HEK cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055975(CHEMBL3325718)
Affinity DataEC50:  1.54E+3nMAssay Description:Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055967(CHEMBL3325714)
Affinity DataIC50: 1.69E+3nMAssay Description:Agonist activity at human delta opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055971(CHEMBL3325696)
Affinity DataEC50:  2.28E+3nMAssay Description:Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055968(CHEMBL3325713)
Affinity DataIC50: 2.65E+3nMAssay Description:Agonist activity at human kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055979(CHEMBL3325712)
Affinity DataEC50:  2.89E+3nMAssay Description:Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055966(CHEMBL3325715)
Affinity DataIC50: 3.30E+3nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production after 30 mins by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055964(CHEMBL3325841)
Affinity DataIC50: 3.38E+3nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production after 30 mins by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055966(CHEMBL3325715)
Affinity DataIC50: 3.38E+3nMAssay Description:Agonist activity at human delta opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055973(CHEMBL3325707)
Affinity DataKi:  3.93E+3nMAssay Description:Displacement of [3H]-naloxone from rat mu opioid receptor expressed in HEK cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055987(CHEMBL3325702)
Affinity DataEC50:  4.72E+3nMAssay Description:Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055967(CHEMBL3325714)
Affinity DataEC50:  5.49E+3nMAssay Description:Agonist activity at myc-tagged mu opioid receptor (unknown origin) expressed in AtT-20 cells assessed as induction of membrane potential hyperpolariz...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055965(CHEMBL3325716)
Affinity DataIC50: 6.00E+3nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production after 30 mins by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055968(CHEMBL3325713)
Affinity DataIC50: 7.89E+3nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production after 30 mins by H...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055982(CHEMBL3325708)
Affinity DataEC50:  8.90E+3nMAssay Description:Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055988(CHEMBL3325701)
Affinity DataEC50:  9.91E+3nMAssay Description:Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055981(CHEMBL3325709)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055968(CHEMBL3325713)
Affinity DataIC50: 1.00E+4nMAssay Description:Agonist activity at human delta opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP production after 30 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055983(CHEMBL3325706)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055980(CHEMBL3325711)
Affinity DataEC50:  1.03E+4nMAssay Description:Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055990(CHEMBL3325699)
Affinity DataEC50:  1.36E+4nMAssay Description:Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055977(CHEMBL3325717)
Affinity DataEC50:  1.36E+4nMAssay Description:Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055985(CHEMBL3325704)
Affinity DataEC50:  1.84E+4nMAssay Description:Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055986(CHEMBL3325703)
Affinity DataEC50:  1.90E+4nMAssay Description:Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055984(CHEMBL3325705)
Affinity DataEC50:  3.02E+4nMAssay Description:Agonist activity at human mu opioid receptor expressed CHO-K1 cells coexpressing Galpha15 assessed as induction of intracellular calcium release by F...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
National Health Research Institutes

Curated by ChEMBL
LigandPNGBDBM50055972(CHEMBL3325710)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]-naloxone from rat mu opioid receptor expressed in HEK cells after 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/31/2016
Entry Details Article
PubMed
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