Compile Data Set for Download or QSAR
maximum 50k data
Found 11 Enz. Inhib. hit(s) with all data for entry = 50045591
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50069756(CHEMBL3407547 | Firsocostat | ND-630 | NDI-010976 ...)
Affinity DataIC50:  1.70nMAssay Description:In vitro inhibition of human recombinant His-tagged ACC2 assessed as malonyl-CoA levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50069756(CHEMBL3407547 | Firsocostat | ND-630 | NDI-010976 ...)
Affinity DataIC50:  2.60nMAssay Description:In vitro inhibition of human recombinant His-tagged ACC1 assessed as malonyl-CoA levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50439637(CHEMBL2419601)
Affinity DataIC50:  11nMAssay Description:Inhibition of human ACC2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50439637(CHEMBL2419601)
Affinity DataIC50:  17nMAssay Description:Inhibition of rat recombinant ACC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Rattus norvegicus (Rat))
Amgen

Curated by ChEMBL
LigandPNGBDBM50314924(6,7-dimethyl-1'-(7-methyl-1H-indazole-5-carbonyl)s...)
Affinity DataIC50:  25nMAssay Description:Inhibition of rat recombinant ACC1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50069758(CHEMBL3407543)
Affinity DataIC50:  50nMAssay Description:Inhibition of human ACC2 assessed as malonyl CoA formation by NADH-linked kinetic methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50069760(CHEMBL3407541)
Affinity DataIC50:  60nMAssay Description:Inhibition of human ACC2 assessed as malonyl CoA formation by NADH-linked kinetic methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50069759(CHEMBL3407542)
Affinity DataIC50:  80nMAssay Description:Inhibition of human ACC2 assessed as malonyl CoA formation by NADH-linked kinetic methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM112919(US8623860, 1.33)
Affinity DataIC50:  180nMAssay Description:Inhibition of human ACC2 assessed as malonyl CoA formation by NADH-linked kinetic methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50394658(CHEMBL2165411)
Affinity DataIC50:  2.80E+3nMAssay Description:In vitro inhibition of human recombinant His-tagged ACC2 assessed as malonyl-CoA levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetyl-CoA carboxylase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50069757(CHEMBL3407545)
Affinity DataIC50:  2.30E+4nMAssay Description:In vitro inhibition of human recombinant His-tagged ACC1 assessed as malonyl-CoA levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed