Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50044991
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040872BDBM50040872(CHEMBL3353189)
Affinity DataIC50: 0.240nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040788BDBM50040788(CHEMBL3353199)
Affinity DataIC50: 0.320nMAssay Description:Inhibition of IRAK4 (unknown origin) by fluorescence polarization based kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040873BDBM50040873(CHEMBL3353188)
Affinity DataIC50: 0.360nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040728BDBM50040728(US9255110, 1 | CHEMBL3353219)
Affinity DataIC50: 1nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040805BDBM50040805(CHEMBL3361255)
Affinity DataKi:  1nMAssay Description:Inhibition of N-terminal GST-fused full-length human IRAK4 (1 to 460 amino acids) assessed as reduction in phosphorylated substrates by Caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040726BDBM50040726(CHEMBL1236126)
Affinity DataKi:  1.20nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040792BDBM50040792(US9546153, ex. 510 | CHEMBL3353195)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of IRAK4 (unknown origin) using fluoresceinated peptide and ATP after 60 mins by by Caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040790BDBM50040790(US9242975, 27 | CHEMBL3353197 | US10227340, Exampl...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of IRAK4 (unknown origin) using fluoresceinated peptide and ATP after 60 mins by by Caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040797BDBM50040797(CHEMBL3353191 | US10023562, Example 14 | US9657009...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of IRAK4 (unknown origin) using fluoresceinated peptide and ATP after 60 mins by by Caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040798BDBM50040798(CHEMBL3353190 | US10023562, Example 12 | US9657009...)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of IRAK4 (unknown origin) using fluoresceinated peptide and ATP after 60 mins by by Caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040868BDBM50040868(CHEMBL3353205)
Affinity DataIC50: 2nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040772BDBM50040772(CHEMBL3353201)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of IRAK4 (unknown origin) by fluorescence polarization based kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040786BDBM50040786(CHEMBL3353200)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of IRAK4 (unknown origin) by fluorescence polarization based kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040791BDBM50040791(CHEMBL3353196)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of IRAK4 (unknown origin) using fluoresceinated peptide and ATP after 60 mins by by Caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040795BDBM50040795(CHEMBL3353193 | US10023562, Example 123 | US965700...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of IRAK4 (unknown origin) using fluoresceinated peptide and ATP after 60 mins by by Caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040796BDBM50040796(CHEMBL3353192 | US10023562, Example 85 | US9657009...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of IRAK4 (unknown origin) using fluoresceinated peptide and ATP after 60 mins by by Caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040794BDBM50040794(CHEMBL3353194 | US9657009, 22 | US10544133, Exampl...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of IRAK4 (unknown origin) using fluoresceinated peptide and ATP after 60 mins by by Caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040793BDBM50040793(US9546153, ex. 79 | CHEMBL3352825)
Affinity DataIC50: 5.60nMAssay Description:Inhibition of IRAK4 (unknown origin) using fluoresceinated peptide and ATP after 60 mins by by Caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040871BDBM50040871(US9221809, 138 | CHEMBL3353202)
Affinity DataIC50: 6nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040806BDBM50040806(CHEMBL3361254)
Affinity DataKi:  7.5nMAssay Description:Inhibition of N-terminal GST-fused full-length human IRAK4 (1 to 460 amino acids) assessed as reduction in phosphorylated substrates by Caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040727BDBM50040727(US9255110, 7 | CHEMBL3353220)
Affinity DataIC50: 8nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040870BDBM50040870(US9221809, 213 | CHEMBL3353203)
Affinity DataIC50: 14nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040869BDBM50040869(CHEMBL3353204)
Affinity DataIC50: 16nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040874BDBM50040874(CHEMBL3353187)
Affinity DataIC50: 21nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040867BDBM50040867(CHEMBL3353206 | US9586948, Example 25)
Affinity DataIC50: 32nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040807BDBM50040807(CHEMBL3361252)
Affinity DataKi:  50nMAssay Description:Inhibition of N-terminal GST-fused full-length human IRAK4 (1 to 460 amino acids) assessed as reduction in phosphorylated substrates by Caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040789BDBM50040789(CHEMBL3353198)
Affinity DataIC50: 50nMAssay Description:Inhibition of IRAK4 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040728BDBM50040728(US9255110, 1 | CHEMBL3353219)
Affinity DataIC50: 55nMAssay Description:Inhibition of IRAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040866BDBM50040866(US9169260, 322 | CHEMBL3353207)
Affinity DataIC50: 100nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040856BDBM50040856(US9169260, 321 | CHEMBL3353208)
Affinity DataIC50: 100nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040809BDBM50040809(US9169260, 320 | CHEMBL3353209)
Affinity DataIC50: 100nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040744BDBM50040744(CHEMBL3353213)
Affinity DataIC50: 100nMAssay Description:Inhibition of IRAK1 (unknown origin) by radiochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040733BDBM50040733(CHEMBL3353215 | US10064861, Compound 20)
Affinity DataIC50: 100nMAssay Description:Inhibition of IRAK1 (unknown origin) by radiochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040734BDBM50040734(CHEMBL3353214)
Affinity DataIC50: 100nMAssay Description:Inhibition of IRAK1 (unknown origin) by radiochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040744BDBM50040744(CHEMBL3353213)
Affinity DataIC50: 100nMAssay Description:Inhibition of IRAK4 (unknown origin) by radiochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040808BDBM50040808(CHEMBL3353210)
Affinity DataIC50: 100nMAssay Description:Inhibition of IRAK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040732BDBM50040732(CHEMBL3353216 | US10064861, Compound 14)
Affinity DataIC50: 100nMAssay Description:Inhibition of IRAK1 (unknown origin) by radiochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040733BDBM50040733(CHEMBL3353215 | US10064861, Compound 20)
Affinity DataIC50: 100nMAssay Description:Inhibition of IRAK4 (unknown origin) by radiochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040734BDBM50040734(CHEMBL3353214)
Affinity DataIC50: 100nMAssay Description:Inhibition of IRAK4 (unknown origin) by radiochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040731BDBM50040731(CHEMBL3353211)
Affinity DataIC50: 100nMAssay Description:Inhibition of IRAK1 (unknown origin) assessed as reduction in biotin tagged phosphorylated peptide substrate1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040732BDBM50040732(CHEMBL3353216 | US10064861, Compound 14)
Affinity DataIC50: 100nMAssay Description:Inhibition of IRAK4 (unknown origin) by radiochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040730BDBM50040730(CHEMBL3353212)
Affinity DataIC50: 100nMAssay Description:Inhibition of IRAK1 (unknown origin) assessed as reduction in biotin tagged phosphorylated peptide substrate1More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040803BDBM50040803(CHEMBL3361257)
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal GST-fused full-length human IRAK4 (1 to 460 amino acids) assessed as reduction in phosphorylated substrates by Caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040804BDBM50040804(CHEMBL3361256)
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal GST-fused full-length human IRAK4 (1 to 460 amino acids) assessed as reduction in phosphorylated substrates by Caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040801BDBM50040801(CHEMBL3353184)
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal GST-fused full-length human IRAK4 (1 to 460 amino acids) assessed as reduction in phosphorylated substrates by Caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040802BDBM50040802(CHEMBL3361258)
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal GST-fused full-length human IRAK4 (1 to 460 amino acids) assessed as reduction in phosphorylated substrates by Caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040799BDBM50040799(CHEMBL3353186)
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal GST-fused full-length human IRAK4 (1 to 460 amino acids) assessed as reduction in phosphorylated substrates by Caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 4(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040800BDBM50040800(CHEMBL3353185)
Affinity DataIC50: 100nMAssay Description:Inhibition of N-terminal GST-fused full-length human IRAK4 (1 to 460 amino acids) assessed as reduction in phosphorylated substrates by Caliper assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040727BDBM50040727(US9255110, 7 | CHEMBL3353220)
Affinity DataIC50: 410nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed
TargetInterleukin-1 receptor-associated kinase 1(Human)
Nimbus Discovery

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50040727BDBM50040727(US9255110, 7 | CHEMBL3353220)
Affinity DataIC50: 983nMAssay Description:Inhibition of IRAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/18/2016
Entry Details Article
PubMed