Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50045534
TargetCysteinyl leukotriene receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066948BDBM50066948(CHEMBL3403187)
Affinity DataIC50: 0.310nMAssay Description:Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066911BDBM50066911(CHEMBL3401689)
Affinity DataIC50: 0.490nMAssay Description:Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066947BDBM50066947(CHEMBL3403186)
Affinity DataIC50: 0.590nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in CHO cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066911BDBM50066911(CHEMBL3401689)
Affinity DataIC50: 0.790nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in CHO cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033085BDBM50033085(CHEMBL3342955)
Affinity DataIC50: 2.5nMAssay Description:Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066947BDBM50066947(CHEMBL3403186)
Affinity DataIC50: 3.40nMAssay Description:Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066942BDBM50066942(CHEMBL3401691)
Affinity DataIC50: 5.70nMAssay Description:Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066908BDBM50066908(CHEMBL3401687)
Affinity DataIC50: 5.70nMAssay Description:Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033085BDBM50033085(CHEMBL3342955)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in CHO cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066952BDBM50066952(CHEMBL3403190)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in CHO cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066946BDBM50066946(CHEMBL3403185)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066909BDBM50066909(CHEMBL3401688)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066941BDBM50066941(CHEMBL3401690)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066941BDBM50066941(CHEMBL3401690)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in CHO cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066948BDBM50066948(CHEMBL3403187)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in CHO cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066952BDBM50066952(CHEMBL3403190)
Affinity DataIC50: 25nMAssay Description:Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066897BDBM50066897(CHEMBL3401686)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066946BDBM50066946(CHEMBL3403185)
Affinity DataIC50: 35nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in CHO cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066897BDBM50066897(CHEMBL3401686)
Affinity DataIC50: 58nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in CHO cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066942BDBM50066942(CHEMBL3401691)
Affinity DataIC50: 70nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in CHO cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066908BDBM50066908(CHEMBL3401687)
Affinity DataIC50: 70nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in CHO cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066951BDBM50066951(CHEMBL3403189)
Affinity DataIC50: 75nMAssay Description:Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066909BDBM50066909(CHEMBL3401688)
Affinity DataIC50: 82nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in CHO cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066950BDBM50066950(CHEMBL3403188)
Affinity DataIC50: 250nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in CHO cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066950BDBM50066950(CHEMBL3403188)
Affinity DataIC50: 370nMAssay Description:Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066945BDBM50066945(CHEMBL3403184)
Affinity DataIC50: 410nMAssay Description:Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066951BDBM50066951(CHEMBL3403189)
Affinity DataIC50: 490nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in CHO cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066945BDBM50066945(CHEMBL3403184)
Affinity DataIC50: 740nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in CHO cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 1(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066944BDBM50066944(CHEMBL3401692)
Affinity DataIC50: 1.90E+3nMAssay Description:Antagonist activity at human CysLT1 receptor expressed in CHO cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed
TargetCysteinyl leukotriene receptor 2(Human)
Ono Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50066944BDBM50066944(CHEMBL3401692)
Affinity DataIC50: 4.30E+3nMAssay Description:Antagonist activity at human CysLT2 receptor expressed in HEK293 cells assessed as inhibition of LTD4-inudced intracellular calcium influx preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2016
Entry Details Article
PubMed