Compile Data Set for Download or QSAR
Report error Found 38 Enz. Inhib. hit(s) with all data for entry = 7033
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 8960BDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 32nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167896BDBM167896(3-(3′-Nitrophenyl)pyrido[2,3-b]pyrazine (6n))
Affinity DataIC50: 466nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167885BDBM167885(3-(3′-Methylphenyl)pyrido[2,3-b]pyrazine (6c...)
Affinity DataIC50: 583nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167888BDBM167888(3-(3′-Fluorophenyl)pyrido[2,3-b]pyrazine (6f...)
Affinity DataIC50: 899nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167890BDBM167890(3-(3′-Chlorophenyl)pyrido[2,3-b]pyrazine (6h...)
Affinity DataIC50: 1.26E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167896BDBM167896(3-(3′-Nitrophenyl)pyrido[2,3-b]pyrazine (6n))
Affinity DataIC50: 1.89E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167895BDBM167895(3-(4′-Nitrophenyl)pyrido[2,3-b]pyrazine (6m))
Affinity DataIC50: 1.97E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167887BDBM167887(3-(4′-Fluorophenyl)pyrido[2,3-b]pyrazine (6e...)
Affinity DataIC50: 2.45E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167891BDBM167891(3-(2′-Chlorophenyl)pyrido[2,3-b]pyrazine (6i...)
Affinity DataIC50: 2.52E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167889BDBM167889(3-(4′-Chlorophenyl)pyrido[2,3-b]pyrazine (6g...)
Affinity DataIC50: 2.59E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167889BDBM167889(3-(4′-Chlorophenyl)pyrido[2,3-b]pyrazine (6g...)
Affinity DataIC50: 2.63E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167897BDBM167897(3-(2′-Nitrophenyl)pyrido[2,3-b]pyrazine (6o))
Affinity DataIC50: 3.00E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167884BDBM167884(3-(4′-Methylphenyl)pyrido[2,3-b]pyrazine (6b...)
Affinity DataIC50: 3.06E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167892BDBM167892(3-(3′-Bromophenyl)pyrido[2,3-b]pyrazine (6j))
Affinity DataIC50: 3.12E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167898BDBM167898(3-(4′-(Piperidin-1-yl)phenyl)pyrido[2,3-b]py...)
Affinity DataIC50: 3.91E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167893BDBM167893(3-(2′-Bromophenyl)pyrido[2,3-b]pyrazine (6k))
Affinity DataIC50: 4.03E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167894BDBM167894(3-(4′-Iodophenyl)pyrido[2,3-b]pyrazine (6l))
Affinity DataIC50: 4.05E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167898BDBM167898(3-(4′-(Piperidin-1-yl)phenyl)pyrido[2,3-b]py...)
Affinity DataIC50: 4.75E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167886BDBM167886(3-(2′-Methylphenyl)pyrido[2,3-b]pyrazine (6d...)
Affinity DataIC50: 5.39E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167899BDBM167899(6,7,8,9-tetrahydropyrido[2,3-b]quinoxaline (6q))
Affinity DataIC50: 5.78E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167885BDBM167885(3-(3′-Methylphenyl)pyrido[2,3-b]pyrazine (6c...)
Affinity DataIC50: 5.88E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 8960BDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 6.41E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167884BDBM167884(3-(4′-Methylphenyl)pyrido[2,3-b]pyrazine (6b...)
Affinity DataIC50: 6.44E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167893BDBM167893(3-(2′-Bromophenyl)pyrido[2,3-b]pyrazine (6k))
Affinity DataIC50: 7.45E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167883BDBM167883(3-Phenylpyrido[2,3-b]pyrazine (6a))
Affinity DataIC50: 9.65E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167891BDBM167891(3-(2′-Chlorophenyl)pyrido[2,3-b]pyrazine (6i...)
Affinity DataIC50: 9.67E+3nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167899BDBM167899(6,7,8,9-tetrahydropyrido[2,3-b]quinoxaline (6q))
Affinity DataIC50: 1.09E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167887BDBM167887(3-(4′-Fluorophenyl)pyrido[2,3-b]pyrazine (6e...)
Affinity DataIC50: 1.12E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167892BDBM167892(3-(3′-Bromophenyl)pyrido[2,3-b]pyrazine (6j))
Affinity DataIC50: 1.15E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167890BDBM167890(3-(3′-Chlorophenyl)pyrido[2,3-b]pyrazine (6h...)
Affinity DataIC50: 1.21E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167895BDBM167895(3-(4′-Nitrophenyl)pyrido[2,3-b]pyrazine (6m))
Affinity DataIC50: 2.08E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167886BDBM167886(3-(2′-Methylphenyl)pyrido[2,3-b]pyrazine (6d...)
Affinity DataIC50: 2.12E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 50022775BDBM50022775(m-Trimethylammoniumphenyldimethylcarbamate | Prost...)
Affinity DataIC50: 2.22E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167897BDBM167897(3-(2′-Nitrophenyl)pyrido[2,3-b]pyrazine (6o))
Affinity DataIC50: 2.23E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167894BDBM167894(3-(4′-Iodophenyl)pyrido[2,3-b]pyrazine (6l))
Affinity DataIC50: 3.12E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167883BDBM167883(3-Phenylpyrido[2,3-b]pyrazine (6a))
Affinity DataIC50: 3.54E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 50022775BDBM50022775(m-Trimethylammoniumphenyldimethylcarbamate | Prost...)
Affinity DataIC50: 4.96E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 167888BDBM167888(3-(3′-Fluorophenyl)pyrido[2,3-b]pyrazine (6f...)
Affinity DataIC50: 7.98E+4nMpH: 8.0 T: 2°CAssay Description:A 96-microliter well plate was used for screening purpose. Each pyridopyrazine derivative was first dissolved in dimethyl sulfoxide to prepare the st...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/3/2016
Entry Details Article
PubMed