Found 22 Enz. Inhib. hit(s) with all data for entry = 50046648 
Affinity DataIC50: 0.200nMAssay Description:Inhibition of EGFR exon19 deletion mutant (unknown origin) by HTRF assay in presence of Km of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 0.200nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) by HTRF assay in presence of Km of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 0.300nMAssay Description:Inhibition of EGFR (unknown origin) by HTRF assay in presence of Km of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 2.40nMAssay Description:Inhibition of EGFR exon19 deletion mutant (unknown origin) by HTRF assay in presence of 2mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 7.60nMAssay Description:Inhibition of EGFR L858R mutant (unknown origin) by HTRF assay in presence of 2 mM of ATPMore data for this Ligand-Target Pair
Affinity DataIC50: >50nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >50nMAssay Description:Inhibition of CYP3A5 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >50nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >50nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >50nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >50nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >50nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >50nMAssay Description:Inhibition of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 65nMAssay Description:Inhibition of EGFR phosphorylation in human H838 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 102nMAssay Description:Inhibition of EGFR (unknown origin) by HTRF assay in presence of 2 mM of ATPMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 156nMAssay Description:Inhibition of recombinant KDR (unknown origin) after 40 mins by scintillation counting analysis in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 622nMAssay Description:Inhibition of recombinant Src (unknown origin) after 40 mins by scintillation counting analysis in presence of [gamma33P]-ATPMore data for this Ligand-Target Pair
Affinity DataIC50: 797nMAssay Description:Inhibition of recombinant D2 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human ERG by patch clamp assayMore data for this Ligand-Target Pair
