TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 1.80nMAssay Description:Inhibition of MEK1 in human HeLa-MaTu matched pair cells assessed as reduction in ERK phosphorylationMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 8.70nMAssay Description:Inhibition of MEK1 in human HeLa-MaTu-ADR matched pair cells assessed as reduction in ERK phosphorylationMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 10nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 11nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of MEK1 in human HeLa-MaTu matched pair cells assessed as reduction in ERK phosphorylationMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 21nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 28nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 31nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 37nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 81nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 94nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 107nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 118nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 127nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 262nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 345nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 379nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
Affinity DataIC50: 530nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 592nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
Affinity DataIC50: 700nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 899nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 941nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of MEK1 (unknown origin) using biotinylated ERK1 as substrate incubated for 2 hrs by fluorescence analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 1(Homo sapiens (Human))
Bayer Healthcare
Curated by ChEMBL
Bayer Healthcare
Curated by ChEMBL
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of MEK1 in human HeLa-MaTu-ADR matched pair cells assessed as reduction in ERK phosphorylationMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human carbonic anhydrase 1More data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human carbonic anhydrase 2More data for this Ligand-Target Pair