Compile Data Set for Download or QSAR
maximum 50k data
Found 23 Enz. Inhib. hit(s) with all data for entry = 50006385
TargetEstrogen receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50180684(4-OHT | Afimoxifene | TamoGel)
Affinity DataIC50:  10nMAssay Description:Antagonist activity at ERalpha in human T47D-KBLuc cells assessed as inhibition of E2-induced transcriptional activity by luciferase reporter gene as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50471252(CHEMBL1222035 | ICI-164384)
Affinity DataIC50:  50nMAssay Description:Antagonist activity at ERalpha in human T47D-KBLuc cells assessed as inhibition of E2-induced transcriptional activity by luciferase reporter gene as...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50499401(CHEMBL3735770)
Affinity DataIC50:  50nMAssay Description:Antagonist activity at luciferase-fused ERalpha in human HEK293 cells expressing eYFP assessed as reduction of E2-induced estrogenic activity after 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50180684(4-OHT | Afimoxifene | TamoGel)
Affinity DataIC50:  70nMAssay Description:Antagonist activity at luciferase-fused ERalpha in human HEK293 cells expressing eYFP assessed as reduction of E2-induced estrogenic activity after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  170nMAssay Description:Inhibition of human recombinant HDAC3 using Boc-Lys(Ac)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetEstrogen receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50499401(CHEMBL3735770)
Affinity DataIC50:  180nMAssay Description:Antagonist activity at ERalpha in human T47D-KBLuc cells assessed as inhibition of E2-induced transcriptional activity by luciferase reporter gene as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50499398(CHEMBL3735995)
Affinity DataIC50:  210nMAssay Description:Antagonist activity at luciferase-fused ERalpha in human HEK293 cells expressing eYFP assessed as reduction of E2-induced estrogenic activity after 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM19410(CHEMBL27759 | MS-275 | US11377423, MS-275 | US1167...)
Affinity DataIC50:  310nMAssay Description:Inhibition of human recombinant HDAC3 using Boc-Lys(Ac)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50471252(CHEMBL1222035 | ICI-164384)
Affinity DataIC50:  340nMAssay Description:Antagonist activity at luciferase-fused ERalpha in human HEK293 cells expressing eYFP assessed as reduction of E2-induced estrogenic activity after 2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  350nMAssay Description:Inhibition of human recombinant HDAC6 using Boc-Lys(Ac)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetEstrogen receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50499400(CHEMBL3735106)
Affinity DataIC50:  510nMAssay Description:Antagonist activity at luciferase-fused ERalpha in human HEK293 cells expressing eYFP assessed as reduction of E2-induced estrogenic activity after 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50499398(CHEMBL3735995)
Affinity DataIC50:  720nMAssay Description:Antagonist activity at ERalpha in human T47D-KBLuc cells assessed as inhibition of E2-induced transcriptional activity by luciferase reporter gene as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50499400(CHEMBL3735106)
Affinity DataIC50:  960nMAssay Description:Inhibition of human recombinant HDAC3 using Boc-Lys(Ac)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50499400(CHEMBL3735106)
Affinity DataIC50:  1.06E+3nMAssay Description:Antagonist activity at ERalpha in human T47D-KBLuc cells assessed as inhibition of E2-induced transcriptional activity by luciferase reporter gene as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50499400(CHEMBL3735106)
Affinity DataIC50:  1.15E+3nMAssay Description:Inhibition of human recombinant HDAC6 using Boc-Lys(Ac)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50499401(CHEMBL3735770)
Affinity DataIC50:  1.55E+3nMAssay Description:Inhibition of human recombinant HDAC3 using Boc-Lys(Ac)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50499399(CHEMBL3735187)
Affinity DataIC50:  2.10E+3nMAssay Description:Antagonist activity at ERalpha in human T47D-KBLuc cells assessed as inhibition of E2-induced transcriptional activity by luciferase reporter gene as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEstrogen receptor(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50499399(CHEMBL3735187)
Affinity DataIC50:  2.55E+3nMAssay Description:Antagonist activity at luciferase-fused ERalpha in human HEK293 cells expressing eYFP assessed as reduction of E2-induced estrogenic activity after 2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50499398(CHEMBL3735995)
Affinity DataIC50:  3.18E+3nMAssay Description:Inhibition of human recombinant HDAC3 using Boc-Lys(Ac)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 3(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50499399(CHEMBL3735187)
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of human recombinant HDAC3 using Boc-Lys(Ac)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50499401(CHEMBL3735770)
Affinity DataIC50:  4.37E+4nMAssay Description:Inhibition of human recombinant HDAC6 using Boc-Lys(Ac)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50499399(CHEMBL3735187)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant HDAC6 using Boc-Lys(Ac)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Mcgill University

Curated by ChEMBL
LigandPNGBDBM50499398(CHEMBL3735995)
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of human recombinant HDAC6 using Boc-Lys(Ac)-AMC as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed