Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 7125
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 8960BDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 19nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175418BDBM175418(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50: 290nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175410BDBM175410(2-[3-cyano-4,6-bis(3-methoxyphenyl)-6-methyl-1,2,5...)
Affinity DataIC50: 1.56E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175415BDBM175415(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50: 2.01E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175416BDBM175416(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50: 2.32E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175419BDBM175419(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50: 2.45E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175416BDBM175416(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50: 2.78E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175413BDBM175413(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50: 4.45E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175417BDBM175417(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50: 5.11E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175406BDBM175406(2-[3-cyano-6-methyl-4,6-bis(3-methylphenyl)-1,2,5,...)
Affinity DataIC50: 5.21E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175411BDBM175411(2-[3-cyano-4,6-bis(4-hydroxyphenyl)-6-methyl-1,2,5...)
Affinity DataIC50: 5.38E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175413BDBM175413(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50: 5.87E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175412BDBM175412(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50: 7.02E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175419BDBM175419(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50: 7.42E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175409BDBM175409(2-[3-cyano-4,6-bis(3-fluorophenyl)-6-methyl-1,2,5,...)
Affinity DataIC50: 8.01E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 8960BDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 8.41E+3nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175408BDBM175408(2-[3-cyano-4,6-bis(4-iodophenyl)-6-methyl-1,2,5,6-...)
Affinity DataIC50: 1.12E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175407BDBM175407(2-[3-cyano-4,6-bis(4-fluorophenyl)-6-methyl-1,2,5,...)
Affinity DataIC50: 1.19E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175405BDBM175405(2-[3-cyano-6-methyl-4,6-bis(4-methylphenyl)-1,2,5,...)
Affinity DataIC50: 1.69E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 50022775BDBM50022775(m-Trimethylammoniumphenyldimethylcarbamate | Prost...)
Affinity DataIC50: 1.93E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175418BDBM175418(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50: 2.03E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175404BDBM175404(2-Dicyanomethylene-6-methyl-4,6-bis(phenyl)-1,2,5,...)
Affinity DataIC50: 2.03E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175414BDBM175414(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50: 2.08E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175412BDBM175412(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50: 2.21E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175406BDBM175406(2-[3-cyano-6-methyl-4,6-bis(3-methylphenyl)-1,2,5,...)
Affinity DataIC50: 3.59E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175405BDBM175405(2-[3-cyano-6-methyl-4,6-bis(4-methylphenyl)-1,2,5,...)
Affinity DataIC50: 3.65E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175415BDBM175415(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50: 3.88E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175417BDBM175417(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50: 3.92E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175411BDBM175411(2-[3-cyano-4,6-bis(4-hydroxyphenyl)-6-methyl-1,2,5...)
Affinity DataIC50: 4.22E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 50022775BDBM50022775(m-Trimethylammoniumphenyldimethylcarbamate | Prost...)
Affinity DataIC50: 4.32E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175408BDBM175408(2-[3-cyano-4,6-bis(4-iodophenyl)-6-methyl-1,2,5,6-...)
Affinity DataIC50: 4.53E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175404BDBM175404(2-Dicyanomethylene-6-methyl-4,6-bis(phenyl)-1,2,5,...)
Affinity DataIC50: 4.81E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175410BDBM175410(2-[3-cyano-4,6-bis(3-methoxyphenyl)-6-methyl-1,2,5...)
Affinity DataIC50: 4.82E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175407BDBM175407(2-[3-cyano-4,6-bis(4-fluorophenyl)-6-methyl-1,2,5,...)
Affinity DataIC50: 5.52E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175414BDBM175414(2-(Cyano(1H-tetrazol-5-yl)methylene)-6-methyl-4,6-...)
Affinity DataIC50: 6.22E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed
TargetCarboxylic ester hydrolase(Horse)
University of Karachi

LigandChemical structure of BindingDB Monomer ID 175409BDBM175409(2-[3-cyano-4,6-bis(3-fluorophenyl)-6-methyl-1,2,5,...)
Affinity DataIC50: 6.88E+4nMpH: 8.0Assay Description:Inhibitory activities of AChE and BChE were evaluated by using the Ellman's method [34]. Herein compounds 2(a-h) and 5(a-h) were evaluated as inh...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2016
Entry Details Article
PubMed