Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50047358
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161874BDBM50161874(CHEMBL3794475)
Affinity DataIC50: 7.60nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50116105BDBM50116105(3-(6-(dimethylamino)-4-methylpyridin-3-yl)-2,5-dim...)
Affinity DataIC50: 8.5nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161832BDBM50161832(CHEMBL3792517)
Affinity DataIC50: 9.5nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161862BDBM50161862(CHEMBL3793568)
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161858BDBM50161858(CHEMBL3793367)
Affinity DataIC50: 12nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161860BDBM50161860(CHEMBL3793322)
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161868BDBM50161868(CHEMBL3793070)
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161958BDBM50161958(CHEMBL3794479)
Affinity DataIC50: 13nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161861BDBM50161861(CHEMBL3792935)
Affinity DataIC50: 14nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161866BDBM50161866(CHEMBL3794030)
Affinity DataIC50: 14nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161841BDBM50161841(CHEMBL3793985)
Affinity DataIC50: 14nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161854BDBM50161854(CHEMBL3794051)
Affinity DataIC50: 15nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161859BDBM50161859(CHEMBL3792636)
Affinity DataIC50: 22nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161867BDBM50161867(CHEMBL3793277)
Affinity DataIC50: 24nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161863BDBM50161863(CHEMBL3793560)
Affinity DataIC50: 65nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161856BDBM50161856(CHEMBL3793190)
Affinity DataIC50: 77nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161851BDBM50161851(CHEMBL3793744)
Affinity DataIC50: 84nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161832BDBM50161832(CHEMBL3792517)
Affinity DataIC50: 88nMAssay Description:Antagonist activity at human CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-stimulated cAMP accumulation after 4 hrs by steady-gl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161853BDBM50161853(CHEMBL3793781)
Affinity DataIC50: 97nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161844BDBM50161844(CHEMBL3793329)
Affinity DataIC50: 140nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161864BDBM50161864(CHEMBL3794050)
Affinity DataIC50: 170nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161857BDBM50161857(CHEMBL3793059)
Affinity DataIC50: 990nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161852BDBM50161852(CHEMBL3793751)
Affinity DataIC50: 2.20E+3nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161855BDBM50161855(CHEMBL3793362)
Affinity DataIC50: 2.50E+3nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161865BDBM50161865(CHEMBL3793845)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50161925BDBM50161925(CHEMBL3793159)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [125I]-CRF from human CRF1 receptor expressed in CHO cellular membrane fraction after 1.5 hrs by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/7/2017
Entry Details Article
PubMed