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Found 137 Enz. Inhib. hit(s) with all data for entry = 50047388
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50397360(CHEMBL2170177 | US10188756, Compound CN110)
Affinity DataIC50:  10nMAssay Description:Inhibition of recombinant HDAC8 (unknown origin) using acetyl-Gly-Ala-(N-acetyl-Lys)-amino-4-methylcoumarin as substrate preincubated for 15 mins fol...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164533(CHEMBL3800182)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164532(CHEMBL3797516)
Affinity DataIC50:  24nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164518(CHEMBL3800394)
Affinity DataIC50:  26nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164516(CHEMBL3800057)
Affinity DataIC50:  29nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164517(CHEMBL3798183)
Affinity DataIC50:  30nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  42nMAssay Description:Inhibition of recombinant human HDAC6 using Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by trypsin addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetHistone deacetylase 8(Schistosoma mansoni)
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164641(CHEMBL3797843)
Affinity DataIC50:  67nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164658(CHEMBL3798268)
Affinity DataIC50:  70nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164518(CHEMBL3800394)
Affinity DataIC50:  75nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164519(CHEMBL3799297)
Affinity DataIC50:  77nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50397360(CHEMBL2170177 | US10188756, Compound CN110)
Affinity DataIC50:  78nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164539(CHEMBL3798870)
Affinity DataIC50:  88nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164517(CHEMBL3798183)
Affinity DataIC50:  90nMAssay Description:Inhibition of recombinant human HDAC6 using Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by trypsin addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164529(CHEMBL3800615)
Affinity DataIC50:  90nMAssay Description:Inhibition of recombinant human HDAC6 using Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by trypsin addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164531(CHEMBL3799246)
Affinity DataIC50:  92nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164517(CHEMBL3798183)
Affinity DataIC50:  96nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164659(CHEMBL3798833)
Affinity DataIC50:  104nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164519(CHEMBL3799297)
Affinity DataIC50:  106nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164538(CHEMBL3797597)
Affinity DataIC50:  116nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
TargetHistone deacetylase 1(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM19149(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Affinity DataIC50:  117nMAssay Description:Inhibition of recombinant human HDAC1 using Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by trypsin addition measured after 20 mins...More data for this Ligand-Target Pair
TargetHistone deacetylase 6(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164641(CHEMBL3797843)
Affinity DataIC50:  120nMAssay Description:Inhibition of recombinant human HDAC6 using Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by trypsin addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164641(CHEMBL3797843)
Affinity DataIC50:  120nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164522(CHEMBL3797442)
Affinity DataIC50:  122nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Schistosoma mansoni)
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164515(CHEMBL3798028)
Affinity DataIC50:  129nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164525(CHEMBL3797455)
Affinity DataIC50:  130nMAssay Description:Inhibition of recombinant human HDAC6 using Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by trypsin addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164514(CHEMBL3799728)
Affinity DataIC50:  140nMAssay Description:Inhibition of recombinant human HDAC6 using Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by trypsin addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164514(CHEMBL3799728)
Affinity DataIC50:  140nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164649(CHEMBL3799897)
Affinity DataIC50:  143nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164520(CHEMBL3798503)
Affinity DataIC50:  146nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164525(CHEMBL3797455)
Affinity DataIC50:  147nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164531(CHEMBL3799246)
Affinity DataIC50:  149nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164513(CHEMBL3800411)
Affinity DataIC50:  150nMAssay Description:Inhibition of recombinant human HDAC6 using Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by trypsin addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164513(CHEMBL3800411)
Affinity DataIC50:  150nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164528(CHEMBL3799183)
Affinity DataIC50:  150nMAssay Description:Inhibition of recombinant human HDAC6 using Cbz-(Ac)Lys-AMC as substrate preincubated for 90 mins followed by trypsin addition measured after 20 mins...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164515(CHEMBL3798028)
Affinity DataIC50:  172nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164597(CHEMBL3798925)
Affinity DataIC50:  178nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164524(CHEMBL3799265)
Affinity DataIC50:  183nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Schistosoma mansoni)
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164539(CHEMBL3798870)
Affinity DataIC50:  190nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164513(CHEMBL3800411)
Affinity DataIC50:  191nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164530(CHEMBL3797232)
Affinity DataIC50:  191nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164538(CHEMBL3797597)
Affinity DataIC50:  204nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164521(CHEMBL3798937)
Affinity DataIC50:  211nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164526(CHEMBL3797939)
Affinity DataIC50:  214nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164516(CHEMBL3800057)
Affinity DataIC50:  220nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164529(CHEMBL3800615)
Affinity DataIC50:  235nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164525(CHEMBL3797455)
Affinity DataIC50:  236nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164520(CHEMBL3798503)
Affinity DataIC50:  240nMAssay Description:Inhibition of recombinant human HDAC8 using Fluor de Lys as substrate preincubated for 90 mins followed by BML-KI176 addition measured after 45 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164662(CHEMBL3799434)
Affinity DataIC50:  267nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Schistosoma mansoni)
Martin-Luther University Of Halle-Wittenberg

Curated by ChEMBL
LigandPNGBDBM50164532(CHEMBL3797516)
Affinity DataIC50:  268nMAssay Description:Inhibition of recombinant Schistosoma mansoni HDAC8 expressed in Escherichia coli using Fluor de Lys as substrate preincubated for 90 mins followed b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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