BindingDB PrimarySearch_ki

Found 116 Enz. Inhib. hit(s) with all data for entry = 50009889

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM50040867(CHEMBL3353206 | US9586948, Example 25)

IC50: 36nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM50040867(CHEMBL3353206 | US9586948, Example 25)

IC50: 36nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM311542(N-(3-carbamoyl-1-methyl- 1H-pyrazol-4-yl)-5- piper...)

IC50: 38nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM311542(N-(3-carbamoyl-1-methyl- 1H-pyrazol-4-yl)-5- piper...)

IC50: 38nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294282(US9586948, Example 1)

IC50: 74nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294282(US9586948, Example 1)

IC50: 74nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294287(US9586948, Example 6)

IC50: 101nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294287(US9586948, Example 6)

IC50: 101nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294310(US9586948, Example 29)

IC50: 106nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294310(US9586948, Example 29)

IC50: 106nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294309(US9586948, Example 28)

IC50: 121nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294309(US9586948, Example 28)

IC50: 121nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294299(US9586948, Example 18)

IC50: 128nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294299(US9586948, Example 18)

IC50: 128nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM50040867(CHEMBL3353206 | US9586948, Example 25)

IC50: 138nMAssay Description:Inhibition of recombinant N-terminal GST-tagged full-length IRAK4 in human THP1-XBlue cells assessed as decrease in NF-kappaB level preincubated for ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM50040867(CHEMBL3353206 | US9586948, Example 25)

IC50: 138nMAssay Description:Inhibition of recombinant N-terminal GST-tagged full-length IRAK4 in human THP1-XBlue cells assessed as decrease in NF-kappaB level preincubated for ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid PDB Similars

Details Article PubMed PDB

3D Structure (crystal)

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM311542(N-(3-carbamoyl-1-methyl- 1H-pyrazol-4-yl)-5- piper...)

IC50: 150nMAssay Description:Inhibition of recombinant N-terminal GST-tagged full-length IRAK4 in human THP1-XBlue cells assessed as decrease in NF-kappaB level preincubated for ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM311542(N-(3-carbamoyl-1-methyl- 1H-pyrazol-4-yl)-5- piper...)

IC50: 150nMAssay Description:Inhibition of recombinant N-terminal GST-tagged full-length IRAK4 in human THP1-XBlue cells assessed as decrease in NF-kappaB level preincubated for ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

PC cid PC sid PDB

Details Article PubMed PDB

3D Structure (crystal)

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294282(US9586948, Example 1)

IC50: 169nMAssay Description:Inhibition of recombinant N-terminal GST-tagged full-length IRAK4 in human THP1-XBlue cells assessed as decrease in NF-kappaB level preincubated for ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294282(US9586948, Example 1)

IC50: 169nMAssay Description:Inhibition of recombinant N-terminal GST-tagged full-length IRAK4 in human THP1-XBlue cells assessed as decrease in NF-kappaB level preincubated for ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294296(US9586948, Example 15)

IC50: 187nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294284(US9586948, Example 3)

IC50: 187nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294284(US9586948, Example 3)

IC50: 187nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294296(US9586948, Example 15)

IC50: 187nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294327(US9586948, Example 46)

IC50: 190nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294327(US9586948, Example 46)

IC50: 190nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294323(US9586948, Example 42)

IC50: 191nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294323(US9586948, Example 42)

IC50: 191nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294310(US9586948, Example 29)

IC50: 202nMAssay Description:Inhibition of recombinant N-terminal GST-tagged full-length IRAK4 in human THP1-XBlue cells assessed as decrease in NF-kappaB level preincubated for ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294310(US9586948, Example 29)

IC50: 202nMAssay Description:Inhibition of recombinant N-terminal GST-tagged full-length IRAK4 in human THP1-XBlue cells assessed as decrease in NF-kappaB level preincubated for ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294293(US9586948, Example 12)

IC50: 212nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294293(US9586948, Example 12)

IC50: 212nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294287(US9586948, Example 6)

IC50: 259nMAssay Description:Inhibition of recombinant N-terminal GST-tagged full-length IRAK4 in human THP1-XBlue cells assessed as decrease in NF-kappaB level preincubated for ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294287(US9586948, Example 6)

IC50: 259nMAssay Description:Inhibition of recombinant N-terminal GST-tagged full-length IRAK4 in human THP1-XBlue cells assessed as decrease in NF-kappaB level preincubated for ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294330(US9586948, Example 49)

IC50: 261nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294330(US9586948, Example 49)

IC50: 261nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294300(US9586948, Example 19)

IC50: 285nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294300(US9586948, Example 19)

IC50: 285nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294299(US9586948, Example 18)

IC50: 294nMAssay Description:Inhibition of recombinant N-terminal GST-tagged full-length IRAK4 in human THP1-XBlue cells assessed as decrease in NF-kappaB level preincubated for ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294299(US9586948, Example 18)

IC50: 294nMAssay Description:Inhibition of recombinant N-terminal GST-tagged full-length IRAK4 in human THP1-XBlue cells assessed as decrease in NF-kappaB level preincubated for ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294309(US9586948, Example 28)

IC50: 307nMAssay Description:Inhibition of recombinant N-terminal GST-tagged full-length IRAK4 in human THP1-XBlue cells assessed as decrease in NF-kappaB level preincubated for ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294309(US9586948, Example 28)

IC50: 307nMAssay Description:Inhibition of recombinant N-terminal GST-tagged full-length IRAK4 in human THP1-XBlue cells assessed as decrease in NF-kappaB level preincubated for ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294303(US9586948, Example 22)

IC50: 401nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294303(US9586948, Example 22)

IC50: 401nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294284(US9586948, Example 3)

IC50: 428nMAssay Description:Inhibition of recombinant N-terminal GST-tagged full-length IRAK4 in human THP1-XBlue cells assessed as decrease in NF-kappaB level preincubated for ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294284(US9586948, Example 3)

IC50: 428nMAssay Description:Inhibition of recombinant N-terminal GST-tagged full-length IRAK4 in human THP1-XBlue cells assessed as decrease in NF-kappaB level preincubated for ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294323(US9586948, Example 42)

IC50: 477nMAssay Description:Inhibition of recombinant N-terminal GST-tagged full-length IRAK4 in human THP1-XBlue cells assessed as decrease in NF-kappaB level preincubated for ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294323(US9586948, Example 42)

IC50: 477nMAssay Description:Inhibition of recombinant N-terminal GST-tagged full-length IRAK4 in human THP1-XBlue cells assessed as decrease in NF-kappaB level preincubated for ...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294298(US9586948, Example 17)

IC50: 478nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

Details Article PubMed

Interleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL

PNG

BDBM294298(US9586948, Example 17)

IC50: 478nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

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