Compile Data Set for Download or QSAR
maximum 50k data
Found 4 Enz. Inhib. hit(s) with all data for entry = 50047878
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50190131(Oblongifolin C)
Affinity DataIC50:  9.00E+3nMAssay Description:Inhibition of human recombinant GST-fused SIRT1 expressed in Escherichia coli DH5-alpha using [3H]acetic acid labeled MPSDKTIGG as substrate after ov...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50190131(Oblongifolin C)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of human recombinant GST-fused SIRT2 expressed in Escherichia coli DH5-alpha using [3H]acetic acid labeled MPSDKTIGG as substrate after ov...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50195222(CHEMBL3894424)
Affinity DataIC50:  3.00E+4nMAssay Description:Inhibition of human SIRT1 preincubated with enzyme followed by Fluor de Lys substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Homo sapiens (Human))
University Of Paris

Curated by ChEMBL
LigandPNGBDBM50195222(CHEMBL3894424)
Affinity DataIC50:  1.50E+5nMAssay Description:Inhibition of human SIRT2 preincubated with enzyme followed by Fluor de Lys substrate addition by fluorescence-based assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed