Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50049123
TargetProthrombin(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50234836BDBM50234836(CHEMBL4086267)
Affinity DataIC50: 0.840nMAssay Description:Inhibition of human thrombin preincubated for 10 mins followed by Ac-FVR-AMC substrate addition measured every 20s for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2019
Entry Details Article
PubMed
TargetProthrombin(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50112086BDBM50112086(CHEMBL48361 | 3-({2-[(4-Carbamimidoyl-phenylamino)...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human thrombin preincubated for 10 mins followed by Ac-FVR-AMC substrate addition measured every 20s for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2019
Entry Details Article
PubMed
TargetProthrombin(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50234838BDBM50234838(CHEMBL4094030)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of human thrombin preincubated for 10 mins followed by Ac-FVR-AMC substrate addition measured every 20s for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2019
Entry Details Article
PubMed
TargetProthrombin(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50234839BDBM50234839(CHEMBL4101764)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human thrombin preincubated for 10 mins followed by Ac-FVR-AMC substrate addition measured every 20s for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2019
Entry Details Article
PubMed
TargetProthrombin(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50234840BDBM50234840(CHEMBL4095408)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human thrombin preincubated for 10 mins followed by Ac-FVR-AMC substrate addition measured every 20s for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2019
Entry Details Article
PubMed
TargetProthrombin(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50234832BDBM50234832(CHEMBL4074973)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of human thrombin preincubated for 10 mins followed by Ac-FVR-AMC substrate addition measured every 20s for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2019
Entry Details Article
PubMed
TargetProthrombin(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50234841BDBM50234841(CHEMBL4102667)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human thrombin preincubated for 10 mins followed by Ac-FVR-AMC substrate addition measured every 20s for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2019
Entry Details Article
PubMed
TargetProthrombin(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50234842BDBM50234842(CHEMBL3740791)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human thrombin preincubated for 10 mins followed by Ac-FVR-AMC substrate addition measured every 20s for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2019
Entry Details Article
PubMed
TargetProthrombin(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50234833BDBM50234833(CHEMBL4076284)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human thrombin preincubated for 10 mins followed by Ac-FVR-AMC substrate addition measured every 20s for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2019
Entry Details Article
PubMed
TargetProthrombin(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50234835BDBM50234835(CHEMBL4078405)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of human thrombin preincubated for 10 mins followed by Ac-FVR-AMC substrate addition measured every 20s for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2019
Entry Details Article
PubMed
TargetProthrombin(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50234834BDBM50234834(CHEMBL4087711)
Affinity DataIC50: 13nMAssay Description:Inhibition of human thrombin preincubated for 10 mins followed by Ac-FVR-AMC substrate addition measured every 20s for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2019
Entry Details Article
PubMed
TargetProthrombin(Human)
Shanghai Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50234837BDBM50234837(CHEMBL4064792)
Affinity DataIC50: 15nMAssay Description:Inhibition of human thrombin preincubated for 10 mins followed by Ac-FVR-AMC substrate addition measured every 20s for 10 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2019
Entry Details Article
PubMed