Compile Data Set for Download or QSAR
maximum 50k data
Found 86 Enz. Inhib. hit(s) with all data for entry = 50049066
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM11863(4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N...)
Affinity DataIC50:  0.0100nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233896(CHEMBL4087855)
Affinity DataIC50:  0.0240nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233883(CHEMBL4094620)
Affinity DataIC50:  0.0260nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233894(CHEMBL4079123)
Affinity DataIC50:  0.0270nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM11863(4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N...)
Affinity DataIC50:  0.0290nMAssay Description:Inhibition of APMA-activated recombinant human MMP-2 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233888(CHEMBL4092215)
Affinity DataIC50:  0.0330nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233878(CHEMBL4059519)
Affinity DataIC50:  0.0340nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233877(CHEMBL4068176)
Affinity DataIC50:  0.0360nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233895(CHEMBL4103367)
Affinity DataIC50:  0.0430nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233880(CHEMBL4090287)
Affinity DataIC50:  0.0540nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233901(CHEMBL4069240)
Affinity DataIC50:  0.0570nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233886(CHEMBL4078492)
Affinity DataIC50:  0.0590nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233884(CHEMBL4086342)
Affinity DataIC50:  0.0620nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233892(CHEMBL4068241)
Affinity DataIC50:  0.0640nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233897(CHEMBL4064516)
Affinity DataIC50:  0.0740nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50203958(CHEMBL3965628)
Affinity DataIC50:  0.0780nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233903(CHEMBL4084468)
Affinity DataIC50:  0.0910nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233879(CHEMBL4095557)
Affinity DataIC50:  0.0930nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM11863(4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N...)
Affinity DataIC50:  0.0970nMAssay Description:Inhibition of APMA-activated recombinant human MMP-8 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233902(CHEMBL4074089)
Affinity DataIC50:  0.100nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM11863(4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N...)
Affinity DataIC50:  0.110nMAssay Description:Inhibition of APMA-activated recombinant human MMP-9 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233885(CHEMBL4104248)
Affinity DataIC50:  0.140nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233900(CHEMBL4083954)
Affinity DataIC50:  0.200nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233882(CHEMBL4079974)
Affinity DataIC50:  0.290nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233893(CHEMBL4102420)
Affinity DataIC50:  0.290nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-1(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM11863(4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N...)
Affinity DataIC50:  0.300nMAssay Description:Inhibition of APMA-activated recombinant human MMP-3 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233881(CHEMBL4098001)
Affinity DataIC50:  0.440nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-2(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM11863(4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N...)
Affinity DataIC50:  0.540nMAssay Description:Inhibition of APMA-activated recombinant human MMP-10 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM11863(4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of APMA-activated recombinant human GST-tagged MMP-14 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofl...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233890(CHEMBL4094673)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233898(CHEMBL4103797)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233889(CHEMBL4073102)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233891(CHEMBL4074167)
Affinity DataIC50:  4.90nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233904(CHEMBL4073581)
Affinity DataIC50:  9.40nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233892(CHEMBL4068241)
Affinity DataIC50:  11nMAssay Description:Inhibition of APMA-activated recombinant human MMP-8 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM11863(4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N...)
Affinity DataIC50:  14nMAssay Description:Inhibition of TACE (unknown origin) using Cy3-PLAQAV(Cy5Q-L-2,3-diaminopropionic acid)-RSSSR-NH2 peptide as substrate measured after 40 mins by spect...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233892(CHEMBL4068241)
Affinity DataIC50:  14nMAssay Description:Inhibition of APMA-activated recombinant human MMP-2 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233888(CHEMBL4092215)
Affinity DataIC50:  21nMAssay Description:Inhibition of APMA-activated recombinant human MMP-8 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233899(CHEMBL4100406)
Affinity DataIC50:  29nMAssay Description:Inhibition of APMA-activated recombinant human MMP-13 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-2(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233892(CHEMBL4068241)
Affinity DataIC50:  30nMAssay Description:Inhibition of APMA-activated recombinant human MMP-10 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM11863(4-({[4-(4-chlorophenoxy)benzene]sulfonyl}methyl)-N...)
Affinity DataIC50:  34nMAssay Description:Inhibition of APMA-activated recombinant human MMP-1 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-2(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233877(CHEMBL4068176)
Affinity DataIC50:  55nMAssay Description:Inhibition of APMA-activated recombinant human MMP-10 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233888(CHEMBL4092215)
Affinity DataIC50:  62nMAssay Description:Inhibition of APMA-activated recombinant human MMP-2 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233893(CHEMBL4102420)
Affinity DataIC50:  76nMAssay Description:Inhibition of APMA-activated recombinant human MMP-8 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233900(CHEMBL4083954)
Affinity DataIC50:  83nMAssay Description:Inhibition of APMA-activated recombinant human MMP-2 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233890(CHEMBL4094673)
Affinity DataIC50:  110nMAssay Description:Inhibition of APMA-activated recombinant human MMP-8 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-2(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233888(CHEMBL4092215)
Affinity DataIC50:  140nMAssay Description:Inhibition of APMA-activated recombinant human MMP-10 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233900(CHEMBL4083954)
Affinity DataIC50:  140nMAssay Description:Inhibition of APMA-activated recombinant human MMP-8 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetStromelysin-2(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233900(CHEMBL4083954)
Affinity DataIC50:  140nMAssay Description:Inhibition of APMA-activated recombinant human MMP-10 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50233877(CHEMBL4068176)
Affinity DataIC50:  180nMAssay Description:Inhibition of APMA-activated recombinant human MMP-2 using Cy3-PLGLK(Cy5Q)AR-NH2 peptide as substrate measured after 40 mins by spectrofluorimetric m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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