Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50049140
TargetTissue factor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50235149(CHEMBL4066780)
Affinity DataIC50: 0.0280nMAssay Description:Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2019
Entry Details Article
PubMed
TargetTissue factor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50235153(CHEBI:67985 | CHEMBL510111)
Affinity DataIC50: 0.0350nMAssay Description:Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2019
Entry Details Article
PubMed
TargetTissue factor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50235152(CHEBI:4747 | CHEMBL230128)
Affinity DataIC50: 0.0540nMAssay Description:Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2019
Entry Details Article
PubMed
TargetTissue factor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50235142(CHEMBL4070749)
Affinity DataIC50: 0.0780nMAssay Description:Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2019
Entry Details Article
PubMed
TargetTissue factor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50235147(Vitalboside A)
Affinity DataIC50: 0.0950nMAssay Description:Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2019
Entry Details Article
PubMed
TargetTissue factor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50234590(CHEMBL4092579)
Affinity DataIC50: 0.221nMAssay Description:Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2019
Entry Details Article
PubMed
TargetTissue factor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346613(Oleanonic Acid | CHEMBL470029)
Affinity DataIC50: 0.221nMAssay Description:Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2019
Entry Details Article
PubMed
TargetTissue factor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50442880(4-Epi-Hederagenin | Hederagenin | US11660306, Exam...)
Affinity DataIC50: 0.221nMAssay Description:Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2019
Entry Details Article
PubMed
TargetTissue factor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50235150(CHEBI:67947 | CHEMBL1910843)
Affinity DataIC50: 0.280nMAssay Description:Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2019
Entry Details Article
PubMed
TargetTissue factor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50235151(CHEMBL4064877)
Affinity DataIC50: 0.640nMAssay Description:Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2019
Entry Details Article
PubMed
TargetTissue factor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50235148(CHEMBL4062123)
Affinity DataIC50: 0.801nMAssay Description:Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2019
Entry Details Article
PubMed
TargetTissue factor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50235154(CHEMBL4080417)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2019
Entry Details Article
PubMed
TargetTissue factor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50246619(benzyl (4aS,6aS,6bR,8aR,10S,12aR,12bR,14bS)-10- hy...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2019
Entry Details Article
PubMed
TargetTissue factor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50346601(Oleanolic acid (OA)(Compound 1) | NSC-114945 | OLE...)
Affinity DataIC50: 5nMAssay Description:Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2019
Entry Details Article
PubMed
TargetTissue factor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50235146(CHEMBL4096910)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2019
Entry Details Article
PubMed
TargetTissue factor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50235144(CHEMBL3343908)
Affinity DataIC50: 9.60nMAssay Description:Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2019
Entry Details Article
PubMed
TargetTissue factor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50235143(CHEMBL2386940)
Affinity DataIC50: 11nMAssay Description:Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2019
Entry Details Article
PubMed
TargetTissue factor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataIC50: 13nMAssay Description:Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2019
Entry Details Article
PubMed
TargetTissue factor(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50235145(CHEMBL3343919)
Affinity DataIC50: 16nMAssay Description:Inhibition of LPS-induced tissue factor procoagulant activity in human THP1 cells preincubated for 1 hr followed by LPS addition measured after 5 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/27/2019
Entry Details Article
PubMed