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Found 12 Enz. Inhib. hit(s) with all data for entry = 50000298
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50090023(4-(3,4-Difluoro-phenyl)-2-oxo-1,2,3,4-tetrahydro-p...)
Affinity DataKi:  0.0700nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50090018(4-(3,4-Difluoro-phenyl)-2-oxo-1,2,3,4-tetrahydro-p...)
Affinity DataKi:  0.130nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50090027((R)-4-(3,4-Difluoro-phenyl)-1,3,6-trimethyl-2-oxo-...)
Affinity DataKi:  0.140nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50245653(CHEMBL4100620)
Affinity DataKi:  0.160nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50245650(CHEMBL4062896)
Affinity DataKi:  0.170nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50090031(4-(3,4-Difluoro-phenyl)-2-oxo-1,2,3,4-tetrahydro-p...)
Affinity DataKi:  0.170nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50245652(CHEMBL4081581)
Affinity DataKi:  0.180nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50090043(4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,...)
Affinity DataKi:  0.240nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50090013(4-(3,4-Difluoro-phenyl)-6-methoxymethyl-2-oxo-1,2,...)
Affinity DataKi:  0.450nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50090041(6-(3,4-Difluoro-phenyl)-5-{3-[4-(4-fluoro-phenyl)-...)
Affinity DataKi:  0.75nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAlpha-1A adrenergic receptor(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50090021(3-Acetyl-4-(3,4-difluoro-phenyl)-1,6-dimethyl-2-ox...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [125I]L-762,459 from recombinant human alpha1a adrenergic receptor expressed in mammalian cells measured after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMelanin-concentrating hormone receptor 1(Homo sapiens (Human))
Indo-Soviet Friendship College of Pharmacy (Isfcp)

Curated by ChEMBL
LigandPNGBDBM50245651(CHEMBL4071004)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]SNAP-7941 from recombinant human MCHR1 expressed in African green monkey COS7 cell membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed